Hippeli S C, Elstner E F
Institut für Botanik und Mikrobiologie, Technische Universität München, Bundesrepublik Deutschland.
Free Radic Res Commun. 1990;11(1-3):29-38. doi: 10.3109/10715769009109665.
Aqueous suspensions of diesel soot particles in combination with sulfite influence certain functions of human polymorphonuclear neutrophils in vitro. Chemiluminescence, generated after activation by opsonized zymosan as well as oxygen uptake were decreased, whereas phagocytosis was increased. An enhancement of degranulation could not be observed. The single substances show little or no effects on the above properties. The results indicate that combinations of air pollutants such as diesel soot and sulfite may modulate vital functions of activated leukocytes in vivo.
柴油烟尘颗粒的水悬浮液与亚硫酸盐相结合，在体外会影响人类多形核中性粒细胞的某些功能。经调理酵母聚糖激活后产生的化学发光以及氧气摄取量均有所下降，而吞噬作用则增强。未观察到脱颗粒作用增强。单一物质对上述特性几乎没有影响。结果表明，诸如柴油烟尘和亚硫酸盐之类的空气污染物组合可能会在体内调节活化白细胞的重要功能。
