Dolan J, Ryan E, Thornhill M, Curran B, Leader M
Department of Pathology, Royal College of Surgeons, Dublin.
Ir J Med Sci. 1990 Aug;159(8):233-6. doi: 10.1007/BF02937374.
Cervical cytology material from 5,815 women who presented to General Practitioners throughout Ireland for routine cervical smears were referred to our Pathology Laboratory. The smears were reviewed retrospectively in order to report on the incidence of dyskaryosis and other abnormalities diagnosed on cervical cytology. Evidence of dyskaryosis was found in a total of 2.2% and "borderline" changes in a total of 0.3% of smears. Cytology and subsequent histology were compared in cases of significant cervical intraepithelial neoplasia. Comparison in cases of moderate and severe dyskaryosis showed precise correlation between the diagnosis of cervical intraepithelial neoplasia on biopsy and its prediction on cytology in 30 of 33 cases. Over a third of women screened were in their 4th decade and the highest incidence of dyskaryosis was in this age group. Only 10% of those screened were 50 years or over and a third were aged 40 years and over. These facts are of relevance with regard to the problem of targeting the population at risk in the long term planning of routine cytology screening services in this country.
来自爱尔兰各地全科医生处进行常规宫颈涂片检查的5815名女性的宫颈细胞学材料被送至我们的病理实验室。对涂片进行回顾性审查，以便报告宫颈细胞学诊断的核异质和其他异常的发生率。在总共2.2%的涂片发现核异质证据，在总共0.3%的涂片发现“临界”变化。对显著宫颈上皮内瘤变病例的细胞学和后续组织学进行了比较。对中度和重度核异质病例的比较显示，在33例病例中的30例中，活检诊断的宫颈上皮内瘤变与其细胞学预测之间存在精确相关性。超过三分之一接受筛查的女性处于40多岁，该年龄组核异质发生率最高。接受筛查的女性中只有10%年龄在50岁及以上，三分之一年龄在40岁及以上。就该国常规细胞学筛查服务的长期规划中针对高危人群的问题而言，这些事实具有相关性。
