INSERM U955, Université Paris 12, Assistance Publique-Hopitaux de Paris, Service de Physiologie, Hôspital Henri Mondor, Créteil, France.
Nanotoxicology. 2010 Mar;4(1):1-14. doi: 10.3109/17435390903428844.
Here, we review several articles of original research published in 2008 that concerned the toxicity of metal and carbon-based nanoparticles. Articles were selected from the MEDLINE PubMed database, all published or pre-published during 2008 and relating to nanomaterials, -particles or -structures and toxicity or health. From the 746 articles, we concentrated on research into carbonaceous (carbon nanotubes [CNTs] and fullerenes) and metallic materials (pure metal, oxides), because these nanomaterials are produced and used worldwide and are the most relevant for public health. Unfortunately, due to the large variability in materials used and methods used conflicting data are generated hampering the risk assessment.
在这里,我们回顾了 2008 年发表的几篇关于金属和碳基纳米粒子毒性的原始研究文章。这些文章选自 MEDLINE PubMed 数据库,均为 2008 年发表或预发表的与纳米材料、纳米颗粒或纳米结构以及毒性或健康有关的文章。在 746 篇文章中,我们主要关注碳质(碳纳米管[CNTs]和富勒烯)和金属材料(纯金属、氧化物)的研究,因为这些纳米材料在世界范围内生产和使用,与公众健康最为相关。不幸的是,由于所用材料的多样性和所用方法的冲突,产生了相互矛盾的数据,这阻碍了风险评估。