普瑞米尔干预措施对健康相关生活质量的影响。
Effects of the PREMIER interventions on health-related quality of life.
机构信息
University of Maryland School of Public Health, College Park, MD 20742, USA.
出版信息
Ann Behav Med. 2010 Dec;40(3):302-12. doi: 10.1007/s12160-010-9220-6.
BACKGROUND
Health-related quality of life (HRQOL) is an important aspect of well-being that may improve with health behavior interventions. However, health behavior change is difficult with pressure to maintain status quo.
PURPOSE
This report examines the effects of two lifestyle interventions and an advice-only condition on HRQOL. Effects of meeting behavioral goals and weight loss also were examined.
METHODS
Participants were 295 men and 467 women (34% African American) with pre-hypertension or stage 1 hypertension from the PREMIER trial. HRQOL was assessed by the Short Form-36. Participants were assigned randomly to (1) advice only (ADVICE), (2) established guidelines for blood pressure control (EST), or (3) established guidelines plus the Dietary Approaches to Stop Hypertension (DASH) dietary pattern (EST + DASH).
RESULTS
Assignment to EST resulted in improvement in three HRQOL subscales at 6 months and one at 18 months relative to ADVICE. EST + DASH improved in two subscales at 6 and 18 months compared with ADVICE. Across conditions, total fat, saturated fat, fruit, and vegetable intake change, along with ≥ 4-kg weight loss, resulted in HRQOL improvements at 6 and 18 months. No improvement was found for change in physical activity, and only a few HRQOL subscales were associated with change in sodium and low-fat dairy intake.
CONCLUSIONS
Intensive lifestyle interventions can result in improvements in HRQOL. Change in dietary intake and weight loss is also important.
背景
健康相关生活质量（HRQOL）是幸福感的一个重要方面，可能随着健康行为干预而改善。然而，在维持现状的压力下，健康行为的改变是困难的。
目的
本报告研究了两种生活方式干预措施和仅提供建议的条件对 HRQOL 的影响。还检查了达到行为目标和减肥的效果。
方法
参与者是来自 PREMIER 试验的 295 名男性和 467 名女性（34%为非裔美国人），患有前期高血压或 1 期高血压。HRQOL 通过 Short Form-36 进行评估。参与者被随机分配到（1）仅建议（ADVICE），（2）血压控制的既定指南（EST），或（3）既定指南加上高血压饮食方法（DASH）饮食模式（EST + DASH）。
结果
与 ADVICE 相比，EST 在 6 个月和 18 个月时在三个 HRQOL 子量表上有所改善，而 EST + DASH 在 6 个月和 18 个月时在两个子量表上有所改善。在所有条件下，总脂肪、饱和脂肪、水果和蔬菜的摄入量变化，以及≥4kg 的体重减轻，在 6 个月和 18 个月时导致 HRQOL 改善。身体活动的变化没有改善，只有少数 HRQOL 子量表与钠和低脂乳制品摄入量的变化相关。
结论
强化生活方式干预可以改善 HRQOL。饮食摄入和体重减轻的变化也很重要。
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