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养育方式与可塑性。

Parenting and plasticity.

机构信息

Department of Psychology and Neuroscience Institute, Princeton University, Princeton NJ 08544, USA.

出版信息

Trends Neurosci. 2010 Oct;33(10):465-73. doi: 10.1016/j.tins.2010.07.003.

DOI:10.1016/j.tins.2010.07.003
PMID:20832872
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3076301/
Abstract

As any new parent knows, having a baby provides opportunities for enrichment, learning and stress - experiences known to change the adult brain. Yet surprisingly little is known about the effects of maternal experience, and even less about the effects of paternal experience, on neural circuitry not directly involved in parenting. Here we discuss how caregiving and the accompanying experiential and hormonal changes influence the hippocampus and prefrontal cortex, brain regions involved in cognition and mood regulation. A better understanding of how parenting impacts the brain is likely to help in devising strategies for treating parental depression, a condition that can have serious cognitive and mental health consequences for children.

摘要

正如任何一位新手父母所知道的,有了孩子会带来丰富的体验、学习机会和压力——这些经历已知会改变成年人的大脑。然而,人们对母亲经验的影响,甚至对父亲经验的影响,知之甚少,这些经验对与育儿不直接相关的神经回路没有影响。在这里,我们讨论了照顾和随之而来的体验和激素变化如何影响海马体和前额叶皮层,这些大脑区域与认知和情绪调节有关。更好地了解育儿如何影响大脑,可能有助于制定治疗父母抑郁的策略,因为这种情况会对孩子的认知和心理健康产生严重后果。

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本文引用的文献

1
Dendritic growth in medial prefrontal cortex and cognitive flexibility are enhanced during the postpartum period.产后阶段中,内侧前额叶皮层的树突生长和认知灵活性增强。
J Neurosci. 2010 Oct 6;30(40):13499-503. doi: 10.1523/JNEUROSCI.3388-10.2010.
2
Paternal recognition of adult offspring mediated by newly generated CNS neurons.成年后代由新生成的中枢神经系统神经元介导的父系识别。
Nat Neurosci. 2010 Jun;13(6):753-8. doi: 10.1038/nn.2550. Epub 2010 May 9.
3
Natural variations in maternal and paternal care are associated with systematic changes in oxytocin following parent-infant contact.母婴护理的自然变化与亲子接触后催产素的系统变化有关。
Psychoneuroendocrinology. 2010 Sep;35(8):1133-41. doi: 10.1016/j.psyneuen.2010.01.013. Epub 2010 Feb 12.
4
Synchronized activity between the ventral hippocampus and the medial prefrontal cortex during anxiety.腹侧海马体和内侧前额叶皮层在焦虑时的同步活动。
Neuron. 2010 Jan 28;65(2):257-69. doi: 10.1016/j.neuron.2009.12.002.
5
Pregnancy decreases oestrogen receptor alpha expression and pyknosis, but not cell proliferation or survival, in the hippocampus.妊娠会降低海马体中的雌激素受体α表达和固缩,但不会影响细胞增殖或存活。
J Neuroendocrinol. 2010 Apr;22(4):248-57. doi: 10.1111/j.1365-2826.2010.01960.x. Epub 2010 Jan 27.
6
Motherhood alters the cellular response to estrogens in the hippocampus later in life.母亲身份会改变晚年海马体中雌激素的细胞反应。
Neurobiol Aging. 2011 Nov;32(11):2091-5. doi: 10.1016/j.neurobiolaging.2009.12.004. Epub 2010 Jan 19.
7
Postpartum depression: what we know.产后抑郁症:我们所知道的。
J Clin Psychol. 2009 Dec;65(12):1258-69. doi: 10.1002/jclp.20644.
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Enhanced maternal aggression and associated changes in neuropeptide gene expression in multiparous rats.经产大鼠母体攻击行为增强及神经肽基因表达的相关变化
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Changes in anxiety and cognition due to reproductive experience: a review of data from rodent and human mothers.由于生殖经验导致的焦虑和认知变化:来自啮齿动物和人类母亲的数据综述。
Neurosci Biobehav Rev. 2010 Mar;34(3):452-67. doi: 10.1016/j.neubiorev.2009.08.011. Epub 2009 Sep 15.
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