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免疫功能正常儿童水痘疫苗病毒再激活致带状疱疹和脑膜炎。

Herpes zoster and meningitis due to reactivation of varicella vaccine virus in an immunocompetent child.

机构信息

Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA.

出版信息

Pediatr Infect Dis J. 2011 Mar;30(3):266-8. doi: 10.1097/INF.0b013e3181f63cf9.

Abstract

Neurologic complications from varicella zoster virus (VZV) reactivation are rare. In this article, we describe a previously immunized child who developed herpes zoster with meningitis. Vaccine strain of VZV was recovered from a skin swab and the cerebrospinal fluid. Reactivation of the vaccine strain of VZV should be recognized as a potential cause of meningitis in children.

摘要

水痘带状疱疹病毒(VZV)再激活引起的神经并发症较为罕见。本文报道了一例既往免疫接种的儿童,其发生带状疱疹并伴有脑膜炎。从皮肤拭子和脑脊液中分离出 VZV 疫苗株。VZV 疫苗株的再激活应被认为是儿童脑膜炎的潜在病因。

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