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一名免疫功能正常儿童因水痘疫苗病毒再激活导致带状疱疹和脑膜炎。

Herpes zoster and meningitis resulting from reactivation of varicella vaccine virus in an immunocompetent child.

作者信息

Iyer Sujit, Mittal Manoj K, Hodinka Richard L

机构信息

The Children's Hospital of Philadelphia, PA 19104-4399, USA.

出版信息

Ann Emerg Med. 2009 Jun;53(6):792-5. doi: 10.1016/j.annemergmed.2008.10.023. Epub 2008 Nov 22.

Abstract

Herpes zoster complicated by meningitis has been mainly reported in immunocompromised patients after reactivation of wild-type varicella-zoster virus. We present one of the first cases of aseptic meningitis after herpes zoster caused by reactivation of vaccine-type varicella-zoster virus in an immunocompetent child. We also highlight the increasing role of both wild-type and vaccine strains of varicella-zoster virus as a cause of viral meningoencephalitis and the use of appropriate laboratory tools to rapidly and accurately identify the virus in order to provide prompt patient care and management.

摘要

带状疱疹并发脑膜炎主要见于免疫功能低下患者,由野生型水痘-带状疱疹病毒再激活所致。我们报告了首例免疫功能正常儿童因疫苗株水痘-带状疱疹病毒再激活引起带状疱疹后发生无菌性脑膜炎的病例。我们还强调了野生型和疫苗株水痘-带状疱疹病毒作为病毒性脑膜脑炎病因的作用日益增加,以及使用适当的实验室工具快速准确地鉴定病毒,以便为患者提供及时的护理和管理。

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