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术前与术中内镜下括约肌切开术治疗胆总管结石。

Preoperative versus intraoperative endoscopic sphincterotomy for management of common bile duct stones.

机构信息

Gastroenterology Surgical Center, Jehan Street, Mansoura, Dakahlia 35516, Egypt.

出版信息

Surg Endosc. 2011 Apr;25(4):1230-7. doi: 10.1007/s00464-010-1348-8. Epub 2010 Sep 17.

Abstract

BACKGROUND

ERCP remains the prevailing method of treating CBDS; however, its ideal timing in respect to laparoscopic cholecystectomy (LC) is not defined. LC combined with intraoperative endoscopic sphincterotomy (IOES) was compared with preoperative endoscopic sphincterotomy (PES) followed by LC for management of preoperatively known cholecystocholedocholithiasis.

METHODS

Between June 2006 and September 2009, 198 patients diagnosed preoperatively by clinical assessment, liver chemistry, ultrasonography, and magnetic resonance cholangiopancreatography (MRCP) to have combined choledochocystolithiasis were eligible. They were randomly divided into two groups: PES/LC group (n = 100) and LC/IOES group (n = 98). The surgical times, surgical success rates, number of stone extractions, postoperative complications, retained common bile duct stones, and postoperative lengths of stay were compared prospectively.

RESULTS

There were no statistically significant differences in surgical time, surgical success rate, CBD diameter, stone size, or stone number between the two groups. The success rate was 95.3% and 97.8% for PES/LC and LC/IOES, respectively. There were no significant difference in postoperative retained stones, surgical time, and complications, but the total hospital stay was significantly shorter in the LC/IOES group.

CONCLUSIONS

PES/LC and LC/IOES are both good options for dealing with preoperatively diagnosed CBDS, but when there is enough experience and facilities, LC/IOES, as a single-stage treatment, would be preferable.

摘要

背景

ERCP 仍然是治疗 CBDS 的主要方法;然而,它与腹腔镜胆囊切除术(LC)的理想时机尚未确定。LC 联合术中内镜下括约肌切开术(IOES)与术前内镜下括约肌切开术(PES)后 LC 治疗术前已知的胆囊胆管结石进行了比较。

方法

2006 年 6 月至 2009 年 9 月,198 例经临床评估、肝功能检查、超声和磁共振胰胆管造影(MRCP)术前诊断为合并性胆总管结石的患者符合条件。他们被随机分为两组:PES/LC 组(n = 100)和 LC/IOES 组(n = 98)。前瞻性比较手术时间、手术成功率、结石取出数量、术后并发症、胆总管残留结石和术后住院时间。

结果

两组在手术时间、手术成功率、CBD 直径、结石大小或结石数量方面无统计学差异。PES/LC 和 LC/IOES 的成功率分别为 95.3%和 97.8%。术后残留结石、手术时间和并发症无显著差异,但 LC/IOES 组总住院时间明显缩短。

结论

PES/LC 和 LC/IOES 都是处理术前诊断为 CBDS 的良好选择,但当有足够的经验和设备时,LC/IOES 作为一种单一阶段的治疗方法更为可取。

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