Kluttig Alexander, Schmidt-Pokrzywniak Andrea
Institut für Klinische Epidemiologie, Martin-Luther-Universität Halle-Wittenberg, Halle (Saale), Germany.
Breast Care (Basel). 2009;4(2):82-87. doi: 10.1159/000211368. Epub 2009 Apr 24.
Although a current decline in breast cancer incidence and mortality is being observed, the disease continues to be the most common malignancy among women. Breast cancer is a worldwide public health problem that causes substantial personal and social burdens. While we do not yet know exactly what causes the disease, we know a large number of risk factors that are linked to breast cancer. In particular, hormonal factors seem to play a key role in the causation of the disease. The aim of this paper is to review the current knowledge of established and suspected risk factors of breast cancer from an epidemiologic point of view.
尽管目前观察到乳腺癌的发病率和死亡率有所下降，但该疾病仍是女性中最常见的恶性肿瘤。乳腺癌是一个全球性的公共卫生问题，会造成巨大的个人和社会负担。虽然我们尚不清楚该疾病的确切病因，但我们知道大量与乳腺癌相关的风险因素。特别是，激素因素似乎在该疾病的病因中起着关键作用。本文的目的是从流行病学角度综述目前关于已确定和疑似乳腺癌风险因素的知识。
