Department of Dental Laboratory Technology, Central Taiwan University of Science and Technology, Taichung City, Taiwan.
J Endod. 2010 Oct;36(10):1683-7. doi: 10.1016/j.joen.2010.07.003. Epub 2010 Aug 21.
The purpose of this study was to comparatively examine physicochemical and biocompatible properties of 20 wt% bismuth oxide (Bi(2)O(3))-containing dicalcium silicate cement and white-colored mineral trioxide aggregate (WMTA).
The radiopacity, setting time, diametral tensile strength, pH value, morphology, and phase composition of the cements with and without Bi(2)O(3) were measured after mixing powders with water. Cement biocompatibility was evaluated by incubating the cement specimens with MG63 human osteoblast-like cells.
The addition of Bi(2)O(3) to the cement led to a significant increase (p < .05) in the setting time of 24 minutes. It was accompanied by a small decrease in the pH value but without adversely affecting diametral tensile strength. The radiopacity value of the Bi(2)O(3)-containing cement was equivalent to 7.3 mm of aluminum, which was significantly higher (p < 0.05) than pure cement without Bi(2)O(3) (1.1 mm of aluminum) but lower (p < .05) than WMTA (9.3 mm of aluminum). However, it was greater than 3 mm of aluminum, which is the value recommended by ISO 6876/2001 standards. MG63 cell viability cultured on Bi(2)O(3)-containing cement was higher than that cultured on WMTA at all culture times.
The dicalcium silicate cement with 20 wt% Bi(2)O(3) showed shortened setting time and good biocompatibility and thus may have the potential to be a root-end filling material alternative to MTA.
本研究旨在比较 20wt%氧化铋(Bi2O3)-硅酸二钙水泥与白色矿化三氧化物聚合体(WMTA)的理化性能和生物相容性。
将粉末与水混合后,测量水泥的射线可探测性、凝固时间、直径拉伸强度、pH 值、形态和相组成。通过将水泥样本与 MG63 人成骨样细胞孵育来评估水泥的生物相容性。
向水泥中添加 Bi2O3 会导致凝固时间显著增加(p <.05)至 24 分钟。这伴随着 pH 值略有下降,但对直径拉伸强度没有不利影响。含 Bi2O3 的水泥的射线可探测值相当于 7.3 毫米的铝,明显高于不含 Bi2O3 的纯水泥(1.1 毫米的铝)(p < 0.05),但低于 WMTA(9.3 毫米的铝)(p <.05)。然而,它大于 ISO 6876/2001 标准推荐的 3 毫米的铝。在所有培养时间,培养在含 Bi2O3 的水泥上的 MG63 细胞活力均高于培养在 WMTA 上的细胞活力。
含 20wt% Bi2O3 的硅酸二钙水泥具有较短的凝固时间和良好的生物相容性,因此可能有潜力成为替代 MTA 的根管封闭材料。