Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
J Am Chem Soc. 2010 Oct 20;132(41):14376-8. doi: 10.1021/ja106869s.
A highly stereoselective and systematic strategy for the introduction of polysulfides in the synthesis of epipolythiodiketopiperazines is described. We report the first total synthesis of dimeric epitri- and epitetrathiodiketopiperazines.
描述了一种在合成表硫代二酮哌嗪中引入多硫化物的高度对映选择性和系统策略。我们报告了二聚体表三硫代和表四硫代二酮哌嗪的首次全合成。