Didier J, Dalens M, Chabanon G, Icart J, Enjalbert L
Biomedicine. 1978 Jan-Feb;28(1):54-62.
Antibodies to EBV induced intracellular antigens, (VCA, EA, NA) and VCA-IgM antibodies have been investigated to define EBV serologic profile of 245 individuals. This profile was a first studied in EBV primary infections. In infectious mononucleosis, the efficiency of EBV serodiagnosis is lower than Paul Bunnel Davidsohn reaction (PBD) : primary infection profile is only characterised in 80% of the positive PBD infectious mononucleosis (IM). On the other hand, EBV antibodies are preponderant for diagnosis in other clinical manifestations of EBV primary-infection were PBD is not alwasy positive (47%). EBV antibodies of patients with various diseases and antibodies of normal subjects show different profiles. By interpretation of these profiles one discuss the possibility to characterize reinfection, and either latent or active persistant infection.
对EB病毒诱导的细胞内抗原（VCA、EA、NA）的抗体以及VCA-IgM抗体进行了研究，以确定245名个体的EB病毒血清学特征。该特征首先在EB病毒原发性感染中进行了研究。在传染性单核细胞增多症中，EB病毒血清诊断的效率低于保罗·邦内尔-大卫索恩反应（PBD）：原发性感染特征仅在80%的PBD阳性传染性单核细胞增多症（IM）中得以体现。另一方面，在EB病毒原发性感染的其他临床表现中，当PBD并非总是呈阳性（47%）时，EB病毒抗体在诊断中占主导地位。患有各种疾病的患者的EB病毒抗体以及正常受试者的抗体呈现出不同的特征。通过对这些特征的解读，人们探讨了区分再感染以及潜伏性或活动性持续性感染的可能性。
