[Effects of compound Centella asiatica enema on kidneys coefficient, electrolytes and blood in chronic renal failure rats].

OBJECTIVE

To study the pharmacological effects of compound Centella asiatica enema on chronic renal failure (CRF) rats.

METHODS

Rats were divided into control group, CRF model group, Niaoduqing positive control group, compound Centella asiatica enema high, middle and low three groups kidney coefficient, electrolyte levels, hematocrit (HCT), red blood cell counts (RBC), hemoglobin (HGB) content were observed after 30 days's treatment.

RESULTS

Compared with the model group, the level of the electrolyte, HCT, RBC, HGB of rats in compound Centella asiatica enema high-doses group and the Niaoduqing group were significantly improved.

CONCLUSION

High-doses of compound Centella asiatica enema has significant therapeutic effect on CRF rats.