Wolfson Medical Vision Laboratory, Department of Engineering Science, University of Oxford, OX1 3PJ Oxford, U.K.
IEEE Trans Med Imaging. 2011 Feb;30(2):351-65. doi: 10.1109/TMI.2010.2078514. Epub 2010 Sep 23.
Positron emission tomography (PET) is a molecular imaging technique which provides important functional information about the human body. However, thoracic PET images are often substantially degraded by respiratory motion, which adversely impacts on subsequent diagnosis. In this paper, a motion correction and attenuation correction method is proposed to correct for motion in respiratory gated PET images and to yield an accurate distribution of the radioactivity concentration. Experimental results show that this method can effectively correct for motion and improve PET image quality. The method is able to provide improved diagnostic information without increasing the acquisition time or the radiation burden.
正电子发射断层扫描(PET)是一种分子成像技术,可提供有关人体的重要功能信息。然而,胸部 PET 图像常常因呼吸运动而严重退化,这会对后续诊断产生不利影响。本文提出了一种运动校正和衰减校正方法,用于校正呼吸门控 PET 图像中的运动,并得出放射性浓度的准确分布。实验结果表明,该方法可以有效地校正运动并提高 PET 图像质量。该方法能够在不增加采集时间或辐射负担的情况下提供改进的诊断信息。