Tobacco Use Research Center, University of Minnesota, 717 Delaware St SE, Minneapolis, Minnesota 55414, USA.
Tob Control. 2010 Oct;19(5):e1-10. doi: 10.1136/tc.2009.035584.
Regulation of nicotine levels in cigarettes and other tobacco products is now possible with the passage of the Family Smoking Prevention and Tobacco Control Act (FSPTCA) in 2009, giving the US Food and Drug Administration (FDA) authority to regulate tobacco products, and with Articles 9-11 of the WHO Framework Convention on Tobacco Control. Both regulatory approaches allow establishing product standards for tobacco constituents, including nicotine. The FSPTCA does not allow nicotine levels to be decreased to zero, although the FDA has the authority to reduce nicotine yields to very low, presumably non-addicting levels. The proposal to reduce levels of nicotine to a level that is non-addicting was originally suggested in 1994. Reduction of nicotine in tobacco products could potentially have a profound impact on reducing tobacco-related morbidity and mortality. To examine this issue, two meetings were convened in the US with non-tobacco-industry scientists of varied disciplines, tobacco control policymakers and representatives of government agencies. This article provides an overview of the current science in the area of reduced nicotine content cigarettes and key conclusions and recommendations for research and policy that emerged from the deliberations of the meeting members.
《家庭吸烟预防及烟草控制法案》（Family Smoking Prevention and Tobacco Control Act，FSPTCA）于 2009 年通过，使美国食品和药物管理局（Food and Drug Administration，FDA）有权监管烟草产品，这标志着通过立法来调节香烟及其他烟草制品中的尼古丁含量成为可能。此外，世界卫生组织《烟草控制框架公约》第 9-11 条也对此加以规定。这两种监管途径都允许制定烟草成分（包括尼古丁）的产品标准。《家庭吸烟预防及烟草控制法案》不允许将尼古丁含量降低至零，但 FDA 有权将尼古丁的释放量降低到非常低的水平，据推测，这种水平是不会让人上瘾的。将尼古丁水平降低到非成瘾水平的提议最初是在 1994 年提出的。降低烟草制品中的尼古丁含量可能会对降低与烟草相关的发病率和死亡率产生深远影响。为了研究这个问题，在美国召集了两次会议，与会者是非烟草行业的具有不同学科背景的科学家、烟草控制政策制定者以及政府机构的代表。本文概述了降低尼古丁含量香烟领域的当前科学，并提供了会议成员审议后得出的关键结论和研究与政策建议。
