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三叶轮生千里光中的两种新黄酮类化合物。

Two new flavones from Tridax procumbens Linn.

机构信息

Nurturing Station for the State Key Laboratory of Subtropical Silviculture, Zhejiang Agriculture and Forestry University, Linan, China.

出版信息

Molecules. 2010 Sep 9;15(9):6357-64. doi: 10.3390/molecules15096357.

DOI:10.3390/molecules15096357
PMID:20877227
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6257746/
Abstract

Two new flavones, 8,3'-dihydroxy-3,7,4'-trimethoxy-6-O-β-D-glucopyranosyl flavone (1) and 6,8,3'-trihydroxy-3,7,4'-trimethoxyflavone (2) were isolated from Tridax procumbens Linn., together with the four known compounds puerarin (3), esculetin (4), oleanolic acid (5) and betulinic acid (6). The structures of the two new flavones were elucidated based on chemical analysis and spectral methods (IR, 1D and 2D NMR, ESI-MS, HR-ESI-MS). The antioxidant activity of the two new flavones were evaluated by two methods, the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and ferric reducing antioxidant power (FRAP) assays, and the data showed that compounds 1 and 2 have certain antioxidant activity, with the antioxidant activity of compound 2 being stronger than that of compound 1.

摘要

从三达龙中分离得到两种新的类黄酮化合物,8,3'-二羟基-3,7,4'-三甲氧基-6-O-β-D-吡喃葡萄糖基黄酮(1)和 6,8,3'-三羟基-3,7,4'-三甲氧基黄酮(2),以及四种已知化合物葛根素(3)、秦皮素(4)、齐墩果酸(5)和桦木酸(6)。根据化学分析和光谱方法(IR、1D 和 2D NMR、ESI-MS、HR-ESI-MS)确定了这两种新类黄酮的结构。通过 1,1-二苯基-2-苦基肼(DPPH)自由基清除活性和铁还原抗氧化能力(FRAP)测定两种方法评估了两种新类黄酮的抗氧化活性,数据表明化合物 1 和 2 具有一定的抗氧化活性,其中化合物 2 的抗氧化活性强于化合物 1。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4321/6257746/f360dac52285/molecules-15-06357-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4321/6257746/a827f36216c7/molecules-15-06357-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4321/6257746/26fc6a55392a/molecules-15-06357-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4321/6257746/efc33788316e/molecules-15-06357-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4321/6257746/f360dac52285/molecules-15-06357-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4321/6257746/a827f36216c7/molecules-15-06357-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4321/6257746/26fc6a55392a/molecules-15-06357-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4321/6257746/efc33788316e/molecules-15-06357-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4321/6257746/f360dac52285/molecules-15-06357-g004.jpg

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Chemical and antibacterial constituents of Skimmia anquetelia.川滇山矾的化学和抗菌成分
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