The Johns Hopkins University, School of Nursing, Baltimore, MD 21205-2110, USA.
Psychooncology. 2011 Apr;20(4):341-51. doi: 10.1002/pon.1754. Epub 2010 Apr 29.
Although a variety of intervention methods have been used to promote Pap test screening among ethnic minority women in the US, the effectiveness of such interventions is unclear. We performed a meta-analysis to examine the overall effectiveness of these interventions in increasing Pap test use by ethnic minority women in the US.
A search of databases (MEDLINE, Cumulative Index to Nursing and Allied Health Literature, PsycINFO, and Science Citation Index-Expanded) and review articles for articles published between 1984 and April 2009 identified 18 randomized and non-randomized controlled trials. The primary study outcome was the difference in the proportion of Pap tests between the treatment and comparison groups.
The pooled mean weighted effect size (d) for the 18 studies was 0.158 (95% confidence interval [CI]=0.100, 0.215), indicating that the interventions were effective in improving Pap test use among ethnic minority women. Among the intervention types, access enhancement yielded the largest effect size (0.253 [95% CI=0.110, 0.397]), followed by community education (0.167 [95% CI=0.057, 0.278]) and individual counseling or letters (0.132 [95% CI=0.069, 0.195]). Combined intervention effects were significant for studies targeting Asian (0.177 [95% CI=0.098, 0.256]) and African American women (0.146 [95% CI=0.028, 0.265]), but not Hispanic women (0.116 [95% CI=-0.008, 0.240]).
Pap test use among ethnic minority women is most likely to increase when access-enhancing strategies are combined. Further research is needed to determine whether more tightly controlled trials of such interventions might reveal an improved rate of cervical cancer screening in Hispanic women as well.
尽管美国已经采用了多种干预方法来促进少数民族妇女进行巴氏涂片检查,但这些干预措施的效果尚不清楚。我们进行了一项荟萃分析,以评估这些干预措施在增加美国少数民族妇女巴氏涂片检查使用率方面的总体效果。
对 1984 年至 2009 年 4 月间发表的文章进行数据库(MEDLINE、护理学和联合健康文献累积索引、PsycINFO 和科学引文索引扩展版)和综述文章检索,以确定 18 项随机和非随机对照试验。主要研究结果是治疗组和对照组之间巴氏涂片检查比例的差异。
18 项研究的合并平均加权效应量(d)为 0.158(95%置信区间[CI]为 0.100,0.215),表明干预措施在提高少数民族妇女的巴氏涂片检查使用率方面是有效的。在干预类型中,增强可及性的效果最大(0.253[95%CI=0.110,0.397]),其次是社区教育(0.167[95%CI=0.057,0.278])和个体咨询或信函(0.132[95%CI=0.069,0.195])。针对亚裔(0.177[95%CI=0.098,0.256])和非裔美国妇女(0.146[95%CI=0.028,0.265])的研究中,联合干预效果显著,但针对西班牙裔妇女(0.116[95%CI=-0.008,0.240])的研究中则不显著。
当增强可及性的策略相结合时,少数民族妇女进行巴氏涂片检查的可能性最大。需要进一步的研究来确定,对这些干预措施进行更严格的对照试验是否也能提高西班牙裔妇女的宫颈癌筛查率。