Adeyemo Wasiu L, Ogunlewe Mobolanle O, Desalu Ibironke, Ladeinde Akinola L, Adeyemo Titilope A, Mofikoya Bolaji O, Hassan Olakunle O, Akanmu Alani S
Departments of Oral and Maxillofacial Surgery, Haematology & Transfusion Medicine, Anaesthesia, Haematology and Blood Transfusion, and Surgery, College of Medicine, University of Lagos.
Indian J Plast Surg. 2010 Jan;43(1):54-9. doi: 10.4103/0970-0358.63967.
The study aims to determine the frequency of homologous blood transfusion in patientsundergoing cleft lip and palate surgery at the Lagos University Teaching Hospital, Nigeria.
A prospective study of transfusion rate in cleft surgery conducted at the Lagos University Teaching Hospital, Nigeria.
One hundred consecutive patients who required cleft lip and palate surgery were recruited into the study. Data collected included age, sex and weight of patients, type of cleft defects, type of surgery done, preoperative haematocrit, duration of surgery, amount of blood loss during surgery, the number of units of blood cross-matched and those used. Each patient was made to donate a unit of homologous blood prior to surgery.
There were 52 females and 48 males with a mean age of 64.4 ± 101.1 months (range, 3-420 months). The most common cleft defect was isolated cleft palate (45%) followed by unilateral cleft lip (28%). Cleft palate repair was the most common procedure (45%) followed by unilateral cleft lip repair (41%). The mean estimated blood loss was 95.8 ± 144.9 ml (range, 2-800ml). Ten (10%) patients (CL=2; CP=5, BCL=1; CLP=2) were transfused but only two of these were deemed appropriate based on percentage blood volume loss. The mean blood transfused was 131.5 ± 135.4ml (range, 35-500ml). Six (60%) of those transfused had a preoperative PCV of < 30%. Only 4.9% of patients who had unilateral cleft lip surgery were transfused as compared with 50% for CLP surgery, 11% for CP surgery, and 10% for bilateral cleft lip surgery.
The frequency of blood transfusion in cleft lip and palate surgery was 10% with a cross-match: transfusion ratio of 10 and transfusion index of 0.1. A "type and screen" policy is advocated for cleft lip and palate surgery.
本研究旨在确定尼日利亚拉各斯大学教学医院接受唇腭裂手术患者的同源输血频率。
在尼日利亚拉各斯大学教学医院对唇腭裂手术输血率进行的前瞻性研究。
连续招募100例需要进行唇腭裂手术的患者进入研究。收集的数据包括患者的年龄、性别和体重、腭裂缺损类型、所做的手术类型、术前血细胞比容、手术持续时间、手术期间的失血量、交叉配血的单位数量和使用的单位数量。每位患者在手术前捐献一个单位的同源血。
有52名女性和48名男性，平均年龄为64.4±101.1个月（范围为3 - 420个月）。最常见的腭裂缺损是孤立性腭裂（45%），其次是单侧唇裂（28%）。腭裂修复是最常见的手术（45%），其次是单侧唇裂修复（41%）。平均估计失血量为95.8±144.9毫升（范围为2 - 800毫升）。10名（10%）患者（唇裂=2例；腭裂=5例；双侧唇裂=1例；唇腭裂=2例）接受了输血，但根据血容量损失百分比仅其中2例被认为是合适的。平均输血量为131.5±135.4毫升（范围为35 - 500毫升）。接受输血的患者中有6例（60%）术前血细胞比容<30%。单侧唇裂手术患者中只有4.9%接受了输血，而唇腭裂手术患者为50%、腭裂手术患者为11%、双侧唇裂手术患者为10%。
唇腭裂手术的输血频率为10%，交叉配血与输血比例为10:1，输血指数为0.1。提倡对唇腭裂手术采用“血型鉴定和筛查”策略。
