Escalona-Arranz Julio César, Péres-Roses Renato, Urdaneta-Laffita Imilci, Camacho-Pozo Miladis Isabel, Rodríguez-Amado Jesús, Licea-Jiménez Irina
Department of Pharmacy, Oriente University, Santiago de Cuba, Cuba.
Pharmacogn Mag. 2010 Jul;6(23):242-7. doi: 10.4103/0973-1296.66944.
Tamarindus indica L. leaves are reported worldwide as antibacterial and antifungal agents; however, this observation is not completely accurate in the case of Cuba. In this article, decoctions from fresh and sun dried leaves, as well as fluid extracts prepared with 30 and 70% ethanol-water and the pure essential oil from tamarind leaves were microbiologically tested against Bacillus subtilis, Enterococcus faecalis, Staphylococcus aureus, Escherichia coli, Salmonella typhimurium, Pseudomona aeruginosa and Candida albicans. Aqueous and fluid extracts were previously characterized by spectrophotometric determination of their total phenols and flavonoids, while the essential oil was chemically evaluated by gas chromatography/mass spectroscopy (GC/MS). Experimental data suggest phenols as active compounds against B. subtilis cultures, but not against other microorganisms. On the other hand, the essential oil exhibited a good antimicrobial spectrum when pure, but its relative low concentrations in common folk preparations do not allow for any good activity in these extracts.
罗望子叶在全球范围内被报道具有抗菌和抗真菌作用;然而,在古巴的情况下,这一观察结果并不完全准确。在本文中,对新鲜和晒干叶片的煎剂、用30%和70%乙醇 - 水制备的液状提取物以及罗望子叶的纯精油针对枯草芽孢杆菌、粪肠球菌、金黄色葡萄球菌、大肠杆菌、鼠伤寒沙门氏菌、铜绿假单胞菌和白色念珠菌进行了微生物学测试。水提取物和液状提取物之前通过分光光度法测定其总酚和黄酮类化合物进行了表征,而精油则通过气相色谱/质谱联用仪(GC/MS)进行了化学评估。实验数据表明酚类是针对枯草芽孢杆菌培养物的活性化合物,但对其他微生物无效。另一方面,精油纯品表现出良好的抗菌谱,但在常见民间制剂中其相对低的浓度使得这些提取物没有任何良好的活性。