Monzote Lianet, García Jesús, González Rosalia, Scotti Marcus Tullius, Setzer William N
Department of Parasitology, Center of Research, Diagnostic and Reference, Institute of Tropical Medicine "Pedro Kouri", Havana 11400, Cuba.
Research Network Natural Products against Neglected Diseases (ResNetNPND), University of Münster, 48149 Münster, Germany.
Plants (Basel). 2021 Nov 19;10(11):2515. doi: 10.3390/plants10112515.
Aromatic plants and essential oils are important agents as complementary and alternative medicines in many cultures and geographical locations. In this review, a literature search on essential oils from Cuba, their chemical compositions, and their pharmacological properties was carried out. Out of 171 published scientific articles on essential oils of Cuban plants, a total of 31 documents, focused on both chemical composition and pharmacological properties, were considered for this review. In general, an increase in articles published in the last decade was noted, particularly in recognized international journals in English. Myrtaceae and Piperaceae were the most representative families collected in the occidental area of the country. Leaves and aerial parts were predominantly used, while a wide and variable number of components were identified, including terpenes, aliphatic derivatives, sulfur-containing compounds, phenylpropanoids, alkaloids and amine-type compounds. Finally, different biological activities were reported such as antiprotozoal, antibacterial, antifungal, cytotoxic, anthelmintic, larvicidal and insecticidal. In conclusion, we encourage further studies that would promote the use of essential oils from Cuban plants in new pharmaceutical products.
在许多文化和地理位置中，芳香植物和精油作为补充和替代药物是重要的药剂。在本综述中，对来自古巴的精油、其化学成分及其药理特性进行了文献检索。在171篇已发表的关于古巴植物精油的科学文章中，本综述共纳入了31篇聚焦于化学成分和药理特性的文献。总体而言，注意到过去十年发表的文章有所增加，特别是在公认的英文国际期刊上。桃金娘科和胡椒科是该国西部地区采集的最具代表性的科。主要使用叶子和地上部分，同时鉴定出种类繁多且各异的成分，包括萜类、脂肪族衍生物、含硫化合物、苯丙素类、生物碱和胺类化合物。最后，报告了不同的生物活性，如抗原虫、抗菌、抗真菌、细胞毒性、驱虫、杀幼虫和杀虫活性。总之，我们鼓励开展进一步研究，以促进古巴植物精油在新药品中的应用。
