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精神分裂症的心理理论表现:诊断、症状及神经心理学关联

Theory of mind performance in schizophrenia: diagnostic, symptom, and neuropsychological correlates.

作者信息

Greig Tamasine C, Bryson Gary J, Bell Morris D

机构信息

Yale University School of Medicine, Department of Psychiatry CMHC, 5th Floor, 34 Park St, New Haven, CT 06519, USA.

出版信息

J Nerv Ment Dis. 2004 Jan;192(1):12-8. doi: 10.1097/01.nmd.0000105995.67947.fc.

DOI:10.1097/01.nmd.0000105995.67947.fc
PMID:14718771
Abstract

The purpose of this study was to explore the relationship between Theory of Mind (ToM) performance and schizophrenia subtype, symptom, and neuropsychological variables. One hundred twenty-eight stable outpatients with schizophrenia or schizoaffective disorder were assessed during the intake phase of a vocational and cognitive rehabilitation study. Results indicate that ToM performance differed significantly by schizophrenia diagnosis, with people diagnosed with disorganized schizophrenia performing the most poorly. Theory of Mind performance was also significantly correlated with measures of thought disorder and verbal memory. Regression analysis revealed that thought disorder and verbal memory measures explained 30% of the variance in ToM scores. Findings suggest that there is theory of mind variance in the schizophrenia population and theory of mind is strongly related to thought disorder, verbal memory, and cognitive disorganization. Contrary to previous reports, ToM was not related to measures of paranoia.

摘要

本研究的目的是探讨心理理论(ToM)表现与精神分裂症亚型、症状及神经心理学变量之间的关系。在一项职业与认知康复研究的入院阶段,对128名患有精神分裂症或分裂情感性障碍的稳定门诊患者进行了评估。结果表明,心理理论表现因精神分裂症诊断而异,被诊断为紊乱型精神分裂症的患者表现最差。心理理论表现也与思维紊乱和言语记忆指标显著相关。回归分析显示,思维紊乱和言语记忆指标解释了心理理论得分中30%的方差。研究结果表明,精神分裂症患者群体中存在心理理论差异,且心理理论与思维紊乱、言语记忆和认知紊乱密切相关。与之前的报告相反,心理理论与偏执指标无关。

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