Björnsson O J, Davídsson D, Olafsson O, Sigfússon N, Porsteinsson P
Acta Med Scand Suppl. 1977;616:1-150.
This report presents the results of serum beta-lipoprotein, total cholesterol and triglycerides determinations in a male population surveyed 1967--'68. This was the first stage (stage I) in a prospective health survey conducted by the Icelandic Health Association. The area of study was the city of Reykjavík with adjacent suburbs and communes. The population invited was 1/3 of each of 16 year-groups of males in the age-interval 34-61 years. The population was selected from the National Roster according to birthdays i.e. the 1st, 4th, 7th,.. of each month, the total number being 2.955. The response was 75.1%. B-lipoproteins were determined with the Hyland Beta-L Test, total cholesterol and triglycerides on Technicon AutoAnalyzer (i) according to Technicon Methodology N-24a, and a modification of the method of Kessler and Lederer respectively. Control sera were run in connection with cholesterol- and triglycerides determinations. Serum cholesterol levels were similar to the highest reported from other countries contrary to the triglycerides levels which are in the low range. The mean values and lower centiles are practically independent of age whereas the higher centiles are markedly age-dependent. A seasonal variation for the cholesterol weekly mean values was found. These values were highest in winter and lowest in summer, the difference estimated to be 30-40 mg%. No seasonal variation of triglycerides was found. Centile-flowdiagrams for these blood lipids are presented and the use of similar flowdiagrams is suggested as an aid to bridge a gap between the interpretation of cross-sectional and longitudinal studies.
本报告展示了1967年至1968年对男性人群进行血清β-脂蛋白、总胆固醇和甘油三酯测定的结果。这是冰岛健康协会进行的一项前瞻性健康调查的第一阶段(第一阶段)。研究区域为雷克雅未克市及其相邻的郊区和公社。邀请的人群是年龄在34至61岁之间的16个男性年龄组中每组的三分之一。该人群根据生日从国家名册中选取,即每月的第1、4、7等日,总数为2955人。应答率为75.1%。β-脂蛋白用海兰德β-L试验测定,总胆固醇和甘油三酯分别在Technicon自动分析仪(i)上根据Technicon方法N-24a以及凯斯勒和莱德勒方法的改良方法进行测定。在进行胆固醇和甘油三酯测定时同时检测对照血清。血清胆固醇水平与其他国家报告的最高水平相似,而甘油三酯水平处于较低范围。平均值和较低百分位数实际上与年龄无关,而较高百分位数则明显依赖于年龄。发现胆固醇每周平均值存在季节性变化。这些值在冬季最高,夏季最低,估计差值为30 - 40mg%。未发现甘油三酯有季节性变化。给出了这些血脂的百分位数流程图,并建议使用类似的流程图来帮助弥合横断面研究和纵向研究解释之间的差距。