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住院慢性精神分裂症患者中五氟利多的评估。

Evaluation of penfluridol in hospitalised chronic schizophrenic.

作者信息

Vaidyalingam N

机构信息

Department of Psychiatry, Govt. Mental Hospital, Madras.

出版信息

J Postgrad Med. 1990 Apr;36(2):100-3.

PMID:2097362
Abstract

Thirty chronic schizophrenic patients completed 12 week treatment with a single weekly dose of 20 mg penfluridol, a new long acting oral neuroleptic. The patients were evaluated by using modified rating scale. Significant reduction in scores was demonstrated in 15 out of 26 symptom variables. Few side effects were reported which were easily controlled by conventional antiparkinson agents. Laboratory investigations remained within normal limits.

摘要

30例慢性精神分裂症患者接受了为期12周的治疗,每周单次服用20毫克五氟利多,这是一种新型长效口服抗精神病药物。采用改良评分量表对患者进行评估。26个症状变量中有15个显示分数显著降低。报告的副作用很少,常规抗帕金森药物很容易控制。实验室检查结果均在正常范围内。

相似文献

1
Evaluation of penfluridol in hospitalised chronic schizophrenic.住院慢性精神分裂症患者中五氟利多的评估。
J Postgrad Med. 1990 Apr;36(2):100-3.
2
Penfluridol in chronic schizophrenia.五氟利多治疗慢性精神分裂症
Acta Psychiatr Belg. 1981 Jul-Aug;81(4):407-15.
3
A long term comparative trial of penfluridol and fluphenazine decanoate in schizophrenic outpatients.五氟利多与癸酸氟奋乃静治疗门诊精神分裂症患者的长期对照试验。
J Clin Psychiatry. 1978 Apr;39(4):375-9.
4
Penfluridol: a long acting oral antipsychotic drug.五氟利多:一种长效口服抗精神病药物。
J Clin Psychiatry. 1979 Feb;40(2):107-9.
5
Comparative short-term evaluation of penfluridol and trifluoperazine in chronic schizophrenia.五氟利多与三氟拉嗪治疗慢性精神分裂症的短期对照研究
Indian J Physiol Pharmacol. 1988 Oct-Dec;32(4):293-8.
6
The treatment of schizophrenia with long-acting oral neuroleptics: a six-month double-blind investigation of penfluridol versus trifluoperazine.
Psychopharmacol Bull. 1977 Jul;13(3):26-7.
7
[Activity of a new neuroleptic, penfluridol (R-16341) in long-term treatments].[一种新型抗精神病药五氟利多(R - 16341)在长期治疗中的活性]
Acta Psiquiatr Psicol Am Lat. 1976 Sep;22(3):205-10.
8
Penfluridol: a double blind trial in chronic schizophrenia.五氟利多:慢性精神分裂症的双盲试验
N Z Med J. 1977 Jan 26;85(580):53-4.
9
A twelve month comparison of penfluridol and trifluoperazine in chronic schizophrenic outpatients.慢性精神分裂症门诊患者中五氟利多与三氟拉嗪的十二个月比较。
J Clin Psychiatry. 1978 Jun;39(6):582-3, 686-8.
10
[Clinical evaluation of penfluridol--a neuroleptic with prolonged action (oral administration) in the treatment of schizophrenic psychoses].五氟利多——一种长效(口服)抗精神病药治疗精神分裂症性精神病的临床评价
Psychiatr Pol. 1978 Sep-Dec;12(5-6):555-62.

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Dopamine Targeting Drugs for the Treatment of Schizophrenia: Past, Present and Future.用于治疗精神分裂症的多巴胺靶向药物:过去、现在与未来
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Penfluridol for schizophrenia.五氟利多治疗精神分裂症。
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