Institute for Clinical and Translational Science, University of Iowa, Iowa City, IA 52242, USA.
J Nutr. 2010 Dec;140(12):2104-15. doi: 10.3945/jn.110.128371. Epub 2010 Oct 27.
Food intake, physical activity (PA), and genetic makeup each affect health and each factor influences the impact of the other 2 factors. Nutrigenomics describes interactions between genes and environment. Knowledge about the interplay between environment and genetics would be improved if experimental designs included measures of nutrient intake and PA. Lack of familiarity about how to analyze environmental variables and ease of access to tools and measurement instruments are 2 deterrents to these combined studies. This article describes the state of the art for measuring food intake and PA to encourage researchers to make their tools better known and more available to workers in other fields. Information presented was discussed during a workshop on this topic sponsored by the USDA, NIH, and FDA in the spring of 2009.
饮食摄入、身体活动(PA)和遗传因素都会影响健康,每个因素都会影响其他两个因素的影响。营养基因组学描述了基因与环境之间的相互作用。如果实验设计包括营养摄入和 PA 的测量,那么对环境和遗传因素之间相互作用的了解将会得到改善。缺乏对如何分析环境变量的熟悉程度以及获取工具和测量仪器的便利性是阻碍这些综合研究的两个因素。本文介绍了测量饮食摄入和 PA 的最新技术,以鼓励研究人员让他们的工具为其他领域的工作者所熟知并更易于获得。在 2009 年春天由美国农业部、美国国立卫生研究院和美国食品和药物管理局主办的关于这个主题的研讨会上讨论了所介绍的信息。