Department of Animal Science, Laboratory of Animal Breeding and Husbandry, Agricultural University of Athens, Iera Odos 75,118 55 Athens, Greece.
Curr Genomics. 2010 May;11(3):168-83. doi: 10.2174/138920210791110960.
Over the second half of 20(th) century much research on lipogenesis has been conducted, especially focused on increasing the production efficiency and improving the quality of animal derived products. However, many diferences are observed in the physiology of lipogenesis between species. Recently, many studies have also elucidated the involvement of numerous genes in this procedure, highlighting diferences not only at physiology but also at the molecular level. The main scope of this review is to point out the major differences between ruminant and non ruminant species, that are observed in key regulatory genes involved in lipogenesis. Human is used as a central reference and according to the findinggs, main differences are analysed. These findings could serve not only as basis for understanding the main physiology of lipogenesis and further basic research, but also as a basis for any animal scientist to develop new concepts and methods for use in improving animal production and modern genetic improvement.
20 世纪后半叶，人们对脂肪生成进行了大量研究，尤其是针对提高动物产品的生产效率和质量。然而，不同物种的脂肪生成生理学存在许多差异。最近，许多研究还阐明了许多基因参与这一过程，不仅突出了生理学上的差异，还突出了分子水平上的差异。本篇综述的主要目的是指出反刍动物和非反刍动物在参与脂肪生成的关键调节基因方面的主要差异。本文以人类为中心参照，并根据研究结果进行了主要差异分析。这些发现不仅可以作为理解脂肪生成主要生理学和进一步基础研究的基础，也可以为任何动物科学家提供新的概念和方法，用于改善动物生产和现代遗传改良。
