基于邻二胺的手性链二烯作为铑（I）催化的高对映选择性共轭加成反应的配体。
Vicinal-diamine-based chiral chain dienes as ligands for rhodium(I)-catalyzed highly enantioselective conjugated additions.
机构信息
Beijing National Laboratory of Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
出版信息
Org Lett. 2010 Dec 3;12(23):5482-5. doi: 10.1021/ol1023536. Epub 2010 Nov 1.
PMID:21038876
Abstract
A variety of readily accessible vicinal-diamine-based chiral chain dienes were successfully synthesized and utilized as steering ligands for rhodium-catalyzed conjugated additions of organoboronic acids to α,β-unsaturated carbonyl compounds to afford the desired adducts in good to excellent yields and ee's.
摘要
成功合成了多种易得的邻二胺基手性链二烯，并将其用作铑催化的有机硼酸与α,β-不饱和羰基化合物的共轭加成反应的手性导向配体，以高至优异的收率和对映选择性得到所需产物。
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