Centre for Pharmaceutical Nanotechnology, Department of Pharmaceutics, National Institute of Pharmaceutical Education & Research, Sector 67, SAS Nagar (Mohali), Punjab, 160062, India.
Nanomedicine (Lond). 2010 Oct;5(8):1277-301. doi: 10.2217/nnm.10.95.
Carbon nanotubes as a unique and novel class of nanomaterials have shown considerable promise in cancer therapy and diagnosis amidst the myriad of nanocarriers. The presence of a large surface area enables the engineering of the surface of nanotubes, thus making them biocompatible, and large benefits can be harnessed from them. Together with their ability to encapsulate small molecules, stacking interactions and conjugation, nanotubes have improved the profile of anticancer agents. The propensity to absorb the body transparent NIR radiation also envisages photothermal and photoacoustic therapy using nanotubes. This article sheds light on the role of carbon nanotubes in cancer therapy and diagnosis based on recent findings.
碳纳米管作为一类独特而新颖的纳米材料，在众多纳米载体中，在癌症治疗和诊断方面显示出了巨大的应用潜力。其较大的比表面积使得纳米管的表面能够进行工程设计，从而使其具有生物相容性，并且可以从它们身上获得巨大的收益。此外，纳米管还能够封装小分子、堆叠相互作用和共轭，从而改善了抗癌药物的特性。碳纳米管还具有吸收人体透明近红外辐射的倾向，因此可以利用纳米管进行光热和光声治疗。本文根据最新研究成果，探讨了碳纳米管在癌症治疗和诊断中的作用。
