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AHD2.0:用于植物系统研究的拟南芥激素数据库的更新版本。

AHD2.0: an update version of Arabidopsis Hormone Database for plant systematic studies.

作者信息

Jiang Zhiqiang, Liu Xiaochuan, Peng Zhiyu, Wan Yinan, Ji Yusi, He Wenrong, Wan Wen, Luo Jingchu, Guo Hongwei

机构信息

National Laboratory of Protein Engineering and Plant Genetic Engineering, College of Life Sciences, Peking University, Beijing 100871, PR China.

出版信息

Nucleic Acids Res. 2011 Jan;39(Database issue):D1123-9. doi: 10.1093/nar/gkq1066. Epub 2010 Nov 2.

Abstract

Phytohormone studies enlightened our knowledge of plant responses to various changes. To provide a systematic and comprehensive view of genes participating in plant hormonal regulation, an online accessible database Arabidopsis Hormone Database (AHD) has been developed, which is a collection of hormone related genes of the model organism Arabidopsis thaliana (AHRGs). Recently we updated our database from AHD to a new version AHD2.0 by adding several pronounced features: (i) updating our collection of AHRGs based on most recent publications as well as constructing elaborate schematic diagrams of each hormone biosynthesis and signaling pathways; (ii) adding orthologs of sequenced plants listed in OrthoMCL-DB to each AHRG in the updated database; (iii) providing predicted miRNA splicing site(s) for each AHRG; (iv) integrating genes that genetically interact with each AHRG according to literatures mining; (v) providing links to a powerful online analysis platform WebLab for the convenience of in-time bioinformatics analysis and (vi) providing links to widely used protein databases and integrating more expression profiling information that would facilitate users for a more systematic and integrative analysis related to phytohormone research.

摘要

植物激素研究增进了我们对植物对各种变化反应的了解。为了系统全面地了解参与植物激素调控的基因,我们开发了一个在线可访问的数据库——拟南芥激素数据库(AHD),它收集了模式生物拟南芥中与激素相关的基因(AHRGs)。最近,我们将数据库从AHD更新到了新版本AHD2.0,增加了几个显著特点:(i)根据最新出版物更新我们的AHRGs集合,并构建每个激素生物合成和信号通路的详细示意图;(ii)将OrthoMCL-DB中列出的已测序植物的直系同源基因添加到更新后的数据库中的每个AHRG中;(iii)为每个AHRG提供预测的miRNA剪接位点;(iv)根据文献挖掘整合与每个AHRG发生遗传相互作用的基因;(v)提供与强大的在线分析平台WebLab的链接,以便及时进行生物信息学分析;(vi)提供与广泛使用的蛋白质数据库的链接,并整合更多表达谱信息,这将有助于用户进行更系统和综合的植物激素研究相关分析。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c1a/3013673/e4f39401e2d7/gkq1066f1.jpg

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