Mehrpour Omid, Sheikhazadi Ardeshir, Ghadyani Mohammad Hasan, Jafarzadeh Mostafa, Hooshyar Hashem
Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran.
J Forensic Leg Med. 2010 Nov;17(8):426-31. doi: 10.1016/j.jflm.2010.08.012. Epub 2010 Oct 6.
Knowledge of the normal range of brain weight is a useful parameter in diagnosis of many pathological conditions. There are racial differences as well as other variables in any population affecting the brain weight. We conducted this study to determine the brain weight in healthy adult Iranian population among both sexes in order to formulate a standard reference range taking into account the variables of age, sex, weight, BMI and height.
MATERIALS & METHODS: Prospective analysis of data from 1308 forensic autopsies of Iranian adults from 23 June 2008 to 22 June 2009 was performed. All subjects were Iranian adults dying of short survival injury time (<15 min) from unnatural deaths who showed no pathological changes.
Brain weight, body weight, body height and BMI were evaluated in 1143 subjects, including 856 males and 287 females, ranging 16-88 years old. Brain weight in males and females was 1322.45 ± 117.05 and 1219.03 ± 127.85 gm respectively (P = 0.001). A negative significant correlation between age and brain weight was seen in both sexes (P = 0.001). Moreover, there was a positive significant correlation between body height and Brain weight in males and females (P = 0.001).
The study indicated higher values in males than females. The observed correlation of brain weight with age, weight and body height was more prominent in females. The results revealed that body height and age in males and body height, weight and age in females may play a predictive role in estimation of brain weight.
了解脑重量的正常范围是诊断多种病理状况的一个有用参数。在任何人群中，脑重量都存在种族差异以及其他影响因素。我们开展这项研究以确定伊朗健康成年人群的脑重量，包括男性和女性，以便综合考虑年龄、性别、体重、体重指数（BMI）和身高这些变量来制定一个标准参考范围。
对2008年6月23日至2009年6月22日期间1308例伊朗成年人法医尸检数据进行前瞻性分析。所有受试者均为伊朗成年人，死于非自然死亡且生存时间短（<15分钟），尸体无病理变化。
对1143名受试者进行了脑重量、体重、身高和BMI评估，其中男性856名，女性287名，年龄范围为16 - 88岁。男性和女性的脑重量分别为1322.45±117.05克和1219.03±127.85克（P = 0.001）。在两性中均观察到年龄与脑重量呈显著负相关（P = 0.001）。此外，男性和女性的身高与脑重量均呈显著正相关（P = 0.001）。
该研究表明男性的脑重量值高于女性。观察到脑重量与年龄、体重和身高的相关性在女性中更为显著。结果显示，男性的身高和年龄以及女性的身高、体重和年龄可能在估计脑重量方面发挥预测作用。
