Department of Physiology, Faculty of Medicine, 50603, University of Malaya, Kuala Lumpur, Malaysia.
Molecules. 2010 Nov 3;15(11):7884-92. doi: 10.3390/molecules15117884.
The antioxidant activity of several Malaysian plant extracts was analyzed simultaneously with their pro-oxidant capacity. This ratio represents an index (ProAntidex) of the net free radical scavenging ability of whole plant extracts. We observed that ethanolic extracts of Nephelium lappaceum peel, Fragaria x ananassa leaf, Lawsonia inermis leaf, Syzygium aqueum leaf and grape seed had a lower Pro-Antidex than the commercially available Emblica™ extract which is an antioxidant agent with very low pro-oxidant activity. Among the aqueous extracts, Lawsonia inermis leaf, Nephelium mutobile leaf and grape seed had lower pro-oxidant activity compared to the Emblica™ extract. Among these extracts, aqueous extract of Nephelium mutobile leaf had a very low index of 0.05 compared to 0.69 for Emblica™. Most of the extracts had a far lower ProAntidex compared to the Vitamin C. The index enables us to identify extracts with high net free radical scavenging activity potential. The ProAntidex is beneficial as a screening parameter to the food industries and healthcare.
同时分析了几种马来西亚植物提取物的抗氧化活性与其促氧化剂能力。该比值代表了植物提取物整体净自由基清除能力的指标（ProAntidex）。我们发现，Nephelium lappaceum 果皮、Fragaria x ananassa 叶、Lawsonia inermis 叶、Syzygium aqueum 叶和葡萄籽的乙醇提取物的 Pro-Antidex 低于市售的具有极低促氧化剂活性的抗氧化剂 Emblica™提取物。在水提取物中，与 Emblica™提取物相比，Lawsonia inermis 叶、Nephelium mutobile 叶和葡萄籽的促氧化剂活性较低。在这些提取物中，与 Emblica™提取物的 0.69 相比，Nephelium mutobile 叶的水提取物的指数非常低，仅为 0.05。与维生素 C 相比，大多数提取物的 ProAntidex 要低得多。该指数可用于识别具有高净自由基清除活性潜力的提取物。ProAntidex 作为筛选参数对食品工业和医疗保健行业非常有益。
