儿童白血病、核设施与人口混居。
Childhood leukaemia, nuclear sites, and population mixing.
机构信息
Cancer Epidemiology Unit, University of Oxford, Richard Doll Building, Headington, Oxford, OX3 7LF, UK.
出版信息
Br J Cancer. 2011 Jan 4;104(1):12-8. doi: 10.1038/sj.bjc.6605982. Epub 2010 Nov 9.
Abstract
The excess of childhood leukaemia (CL) in Seascale, near the Sellafield nuclear reprocessing site in rural NW England, suggested that an epidemic of an underlying infection, to which CL is a rare response, is promoted by marked population mixing (PM) in rural areas, in which the prevalence of susceptibles is higher than average. This hypothesis has been confirmed by 12 studies in non-radiation situations. Of the five established CL excesses near nuclear sites, four are associated with significant PM; in the fifth, the Krummel power station in Germany, the subject has not been thoroughly investigated.
摘要
在英格兰西北部农村地区的塞拉菲尔德核再处理厂址附近的锡斯尔凯斯，儿童白血病（CL）的发病率过高，这表明一种潜在感染的流行（CL 是这种感染的罕见反应），是由农村地区的明显人口混合（PM）所促进的，在这种情况下，易感人群的流行率高于平均水平。这一假设已被 12 项非辐射情况下的研究证实。在五个已确定的靠近核设施的 CL 发病率过高的地方中，有四个与显著的 PM 有关；在德国的克鲁梅尔发电站，这一问题尚未得到彻底调查。
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