van Brakel Wim, Cross Hugh, Declercq Etienne, Deepak Sunil, Lockwood Diana, Saunderson Paul, Smith W Cairns, Batty Jenny, Nahodilova Lenka, Soutar Doug, Augustine Valsa, Ebenso Bassey
Lepr Rev. 2010 Sep;81(3):228-75.
The ILEP Technical Commission (ITC) advises ILEP member associations on technical aspects of leprosy. A major review of research evidence in leprosy was published prior to the International Leprosy Congress in 2002. This current report updates that review based on research published between 2002-2009 and focuses on interventions for prevention, early diagnosis, chemotherapy, reactions, prevention of disability, stigma measurement and reduction and rehabilitation in leprosy.
A systematic search of electronic databases of published literature for systematic reviews, controlled trials and ongoing trials was conducted in July 2009. The search identified 13 reviews and 21 controlled trials. The data from these studies were extracted and the references cited by these studies reviewed. Each member of the ITC took responsibility to review this evidence for each of the 7 topics and prepared a report summarising the evidence and making recommendations. These findings were presented and discussed at a Forum held in London in March 2010. The report was finalised following this Forum. The evidence was graded using a standard grading system for levels of evidence. However for some topics the evidence used qualitative and other designs which do no conform to this grading but was considered relevant and appropriate.
国际麻风防治协会技术委员会（ITC）就麻风病的技术问题向国际麻风防治协会成员协会提供建议。2002年国际麻风病大会召开之前，曾发表过一份关于麻风病研究证据的重要综述。本报告在2002年至2009年期间发表的研究基础上更新了该综述，重点关注麻风病预防、早期诊断、化疗、反应、残疾预防、耻辱感测量与减少以及康复方面的干预措施。
2009年7月对已发表文献的电子数据库进行了系统检索，以查找系统评价、对照试验和正在进行的试验。检索确定了13篇综述和21项对照试验。提取了这些研究的数据，并对这些研究引用的参考文献进行了审查。ITC的每位成员负责审查这7个主题中每个主题的证据，并编写一份总结证据并提出建议的报告。这些研究结果在2010年3月于伦敦举行的一次论坛上进行了展示和讨论。该报告在此次论坛之后定稿。证据采用标准的证据分级系统进行分级。然而，对于某些主题，证据采用了定性和其他不符合该分级但被认为相关且适当的设计。
