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运动和身体活动对抑郁的影响。

Effects of exercise and physical activity on depression.

机构信息

Department of Sport and Exercise Science, University of Thessaly, TEFAA Karies, Trikala 42100, Greece.

出版信息

Ir J Med Sci. 2011 Jun;180(2):319-25. doi: 10.1007/s11845-010-0633-9. Epub 2010 Nov 14.

DOI:10.1007/s11845-010-0633-9
PMID:21076975
Abstract

INTRODUCTION

Depression is a very prevalent mental disorder affecting 340 million people globally and is projected to become the leading cause of disability and the second leading contributor to the global burden of disease by the year 2020.

AIM

In this paper, we review the evidence published to date in order to determine whether exercise and physical activity can be used as therapeutic means for acute and chronic depression. Topics covered include the definition, classification criteria and treatment of depression, the link between β-endorphin and exercise, the efficacy of exercise and physical activity as treatments for depression, properties of exercise stimuli used in intervention programs, as well as the efficacy of exercise and physical activity for treating depression in diseased individuals.

CONCLUSIONS

The presented evidence suggests that exercise and physical activity have beneficial effects on depression symptoms that are comparable to those of antidepressant treatments.

摘要

引言

抑郁症是一种非常普遍的精神障碍,影响着全球 3.4 亿人,预计到 2020 年,它将成为残疾的主要原因,并成为全球疾病负担的第二大主要贡献者。

目的

本文综述了迄今为止发表的证据,以确定运动和体育活动是否可以作为治疗急性和慢性抑郁症的手段。涵盖的主题包括抑郁症的定义、分类标准和治疗、β-内啡肽与运动的关系、运动和体育活动治疗抑郁症的疗效、干预计划中使用的运动刺激的特性,以及运动和体育活动治疗患病个体抑郁症的疗效。

结论

所呈现的证据表明,运动和体育活动对抑郁症状有有益的影响,与抗抑郁治疗的效果相当。

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Interaction between serotonin 5-HT1A receptors and beta-endorphins modulates antidepressant response.血清素5-HT1A受体与β-内啡肽之间的相互作用调节抗抑郁反应。
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Influence of beta-Endorphin on anxious behavior in mice: interaction with EtOH.β-内啡肽对小鼠焦虑行为的影响:与乙醇的相互作用。
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Mechanistic intersections between migraine and major depressive disorder.偏头痛与重度抑郁症之间的机制交叉点。
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