Gunawardene R D, Davenport H T
Department of Anaesthesia, Northwick Park Hospital, Harrow, Middlesex.
Anaesthesia. 1990 Jan;45(1):52-4. doi: 10.1111/j.1365-2044.1990.tb14506.x.
One hundred unpremedicated fit day surgery patients aged between 27 and 68 years were allocated randomly into one of four groups and EMLA, glyceryl trinitrate, EMLA and glyceryl trinitrate or a placebo ointment was applied to the dorsum of a hand. The pain and ease of venepuncture were determined at induction of anaesthesia 60 minutes later. Pain scores were also reassessed 1-2 hours after operation. Lower pain scores and easier venepuncture occurred when EMLA and glyceryl trinitrate ointment was applied to the dorsum of the hand.
100名年龄在27至68岁之间、未接受术前用药的健康日间手术患者被随机分为四组，分别在其手背涂抹复方利多卡因乳膏、硝酸甘油、复方利多卡因乳膏和硝酸甘油或安慰剂软膏。60分钟后麻醉诱导时测定静脉穿刺的疼痛程度和难易程度。术后1至2小时也重新评估疼痛评分。在手背涂抹复方利多卡因乳膏和硝酸甘油软膏时，疼痛评分较低，静脉穿刺也更容易。
