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Onset time of topical analgesia with EMLA 5%: no reduction with glyceryl trinitrate.

作者信息

Nott M R, Clemson C J, Peacock J L

机构信息

Royal West Sussex Hospital, Chichester, United Kingdom.

出版信息

Eur J Anaesthesiol. 1996 Jan;13(1):17-20. doi: 10.1097/00003643-199601000-00004.

DOI:10.1097/00003643-199601000-00004
PMID:8829930
Abstract

Many adults are distressed by painful investigations or treatment, including venepuncture. The early effects of Eutectic Mixture of Local Anaesthetics (EMLA) 5%, on relief of pinprick pain in the antecubital area was investigated and compared with EMLA plus glyceryl trinitrate and with a placebo cream in 100 patients. Topical analgesia after application of EMLA developed within 5 min in 69% and within 10 min in 83% of those tested, significantly different from placebo, (P = 0.01).

摘要

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