Cariology and Operative Dentistry, Department of Restorative Sciences, Graduate School, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113-8549, Japan.
J Dent Res. 2011 Feb;90(2):246-50. doi: 10.1177/0022034510387793. Epub 2010 Nov 17.
Bioglass 45S5 is a bioactive glass that can create a layer of calcium-phosphate crystals on mineralized hard tissues. In this study, 45S5 bioglass was mixed with phosphoric acid and irradiated with CO(2) laser and examined as a possible aid in the treatment of dentin hypersensitivity. The dentinal surface modified by the aforementioned technique was chemically and micro-morphologically examined with a field emission scanning electron microscope (FE-SEM) equipped with an energy-dispersive x-ray spectroscope (EDS), and the crystalline structures of the examined dentinal surfaces were examined by x-ray diffraction (XRD). Moreover, the mechanical properties of the newly formed layer were examined by nanoindentation. The results showed that 45S5 bioglass could occlude the dentinal tubule orifices with calcium-phosphate crystals. The application of CO(2) laser potentially improved the mechanical organization of these crystals.
45S5 生物玻璃是一种具有生物活性的玻璃，能够在矿化的硬组织上形成一层钙磷晶体。在这项研究中，将 45S5 生物玻璃与磷酸混合，用 CO(2)激光辐照，并作为治疗牙本质过敏症的一种可能辅助手段进行了研究。用配备能量色散 X 射线光谱仪（EDS）的场发射扫描电子显微镜（FE-SEM）对上述技术处理后的牙本质表面进行了化学和微观形貌检查，并通过 X 射线衍射（XRD）检查了检查过的牙本质表面的晶体结构。此外，通过纳米压痕法检查了新形成层的机械性能。结果表明，45S5 生物玻璃可以用钙磷晶体堵塞牙本质小管口。CO(2)激光的应用可能改善了这些晶体的机械组织。
