School of Medicine and Public Health, The University of Newcastle, Newcastle, NSW, Australia.
Age Ageing. 2011 Jan;40(1):42-9. doi: 10.1093/ageing/afq134. Epub 2010 Nov 17.
the diagnosis and management of obstructive airway diseases (OADs) such as asthma and chronic obstructive pulmonary disease (COPD) can be challenging in older people.
to assess the clinical, functional, biological and behavioural characteristics relevant to the management of older people with OAD.
a cross-sectional study was conducted in a tertiary teaching hospital. Older people (> 55 years) (n = 100) with an OAD underwent a multidimensional assessment (MDA) involving questionnaires, clinical assessments, physiological measurements and biomarkers.
the assessment identified a mean (SD) of 11.3 (2.5) clinical management issues and 3.1 (1.8) comorbid conditions per participant. Common problems were: airways hyper-responsiveness (80%); airway inflammation (74%); activity limitation (74%) and systemic inflammation (60.5%). The number and type of issues were similar irrespective of a diagnosis of asthma or COPD (P = 0.2). The degree of health status impairment correlated significantly with the number of clinical management issues detected (r = 0.59; P < 0.0001).
older people with OAD experience multiple clinical issues that adversely impact their health status. The number and type are similar irrespective of diagnosis. This MDA identifies significant clinical issues that may not be addressed in a diagnosis centred approach suggesting that a multidisciplinary approach is necessary when assessing and managing older people with OAD.
在老年人中,诊断和管理阻塞性气道疾病(OAD),如哮喘和慢性阻塞性肺疾病(COPD),可能具有挑战性。
评估与 OAD 老年人管理相关的临床、功能、生物学和行为特征。
在一家三级教学医院进行了一项横断面研究。患有 OAD 的老年人(>55 岁)(n=100)接受了多维评估(MDA),包括问卷调查、临床评估、生理测量和生物标志物。
评估确定了每位参与者平均(SD)有 11.3(2.5)个临床管理问题和 3.1(1.8)种合并症。常见问题包括:气道高反应性(80%);气道炎症(74%);活动受限(74%)和全身炎症(60.5%)。无论诊断为哮喘还是 COPD,问题的数量和类型都相似(P=0.2)。健康状况受损程度与检测到的临床管理问题数量显著相关(r=0.59;P<0.0001)。
患有 OAD 的老年人会经历多种影响其健康状况的临床问题。无论诊断如何,数量和类型都相似。这种 MDA 确定了可能未在以诊断为中心的方法中解决的重要临床问题,这表明在评估和管理患有 OAD 的老年人时需要多学科方法。