Tulsiani S M, Lau C L, Graham G C, Van Den Hurk A F, Jansen C C, Smythe L D, McKay D B, Craig S B
WHO/OIE/FAO Collaborating Centre for Reference and Research on Leptospirosis, Communicable Diseases Unit, Queensland Health Forensic and Scientific Services, P.O. Box 594, Archerfield, Queensland, 4108, Australia.
Ann Trop Med Parasitol. 2010 Oct;104(7):543-56. doi: 10.1179/136485910X12851868779867.
Human leptospirosis is a zoonotic disease of global importance that causes significant morbidity and mortality, particularly in developing nations. In this review, the history, epidemiology, transmission, clinical presentation and treatment of this disease, and its impact in Australia, are discussed. Central to this review is the delineation of diagnostic methods for the disease and the challenges that this disease presents for both the clinician and diagnostic laboratory. This information should furnish clinicians with an updated tool to help overcome a number of problems associated with the diagnosis of leptospirosis.
人类钩端螺旋体病是一种具有全球重要性的人畜共患病，会导致严重的发病和死亡，尤其是在发展中国家。在这篇综述中，将讨论该疾病的历史、流行病学、传播、临床表现、治疗及其在澳大利亚的影响。本综述的核心是阐述该疾病的诊断方法以及该疾病给临床医生和诊断实验室带来的挑战。这些信息应为临床医生提供一种最新工具，以帮助克服与钩端螺旋体病诊断相关的一些问题。
