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退休对主要慢性疾病和疲劳的影响:法国 GAZEL 职业队列研究。

Effect of retirement on major chronic conditions and fatigue: French GAZEL occupational cohort study.

机构信息

Stress Research Institute, Stockholm University, SE-106 91 Stockholm, Sweden.

出版信息

BMJ. 2010 Nov 23;341:c6149. doi: 10.1136/bmj.c6149.

Abstract

OBJECTIVES

To determine, using longitudinal analyses, if retirement is followed by a change in the risk of incident chronic diseases, depressive symptoms, and fatigue. Design Prospective study with repeat measures from 7 years before to 7 years after retirement.

SETTING

Large French occupational cohort (the GAZEL study), 1989-2007. Participants 11 246 men and 2858 women.

MAIN OUTCOME MEASURES

Respiratory disease, diabetes, coronary heart disease and stroke, mental fatigue, and physical fatigue, measured annually by self report over the 15 year observation period; depressive symptoms measured at four time points.

RESULTS

The average number of repeat measurements per participant was 12.1. Repeated measures logistic regression with generalised estimating equations showed that the cumulative prevalence of self reported respiratory disease, diabetes, and coronary heart disease and stroke increased with age, with no break in the trend around retirement. In contrast, retirement was associated with a substantial decrease in the prevalence of both mental fatigue (odds ratio for fatigue one year after versus one year before retirement 0.19, 95% confidence interval 0.18 to 0.21) and physical fatigue (0.27, 0.26 to 0.30). A major decrease was also observed in depressive symptoms (0.60, 0.53 to 0.67). The decrease in fatigue around retirement was more pronounced among people with a chronic disease before retirement.

CONCLUSIONS

Longitudinal modelling of repeat data showed that retirement did not change the risk of major chronic diseases but was associated with a substantial reduction in mental and physical fatigue and depressive symptoms, particularly among people with chronic diseases.

摘要

目的

通过纵向分析,确定退休是否会改变新发慢性疾病、抑郁症状和疲劳的风险。

设计

前瞻性研究,重复测量时间为退休前 7 年至退休后 7 年。

地点

大型法国职业队列(GAZEL 研究),1989-2007 年。

参与者

11246 名男性和 2858 名女性。

主要结局指标

呼吸系统疾病、糖尿病、冠心病和中风、精神疲劳和身体疲劳,通过 15 年观察期内的自我报告每年进行测量;抑郁症状在四个时间点进行测量。

结果

每位参与者的平均重复测量次数为 12.1 次。使用广义估计方程的重复测量逻辑回归显示,自我报告的呼吸系统疾病、糖尿病和冠心病和中风的累积患病率随年龄增长而增加,退休前后趋势没有中断。相比之下,退休与精神疲劳(退休后一年与退休前一年疲劳的比值为 0.19,95%置信区间为 0.18 至 0.21)和身体疲劳(0.27,0.26 至 0.30)的患病率显著下降有关。抑郁症状也显著下降(0.60,0.53 至 0.67)。在退休前后,患有慢性疾病的人群中疲劳的下降更为明显。

结论

重复数据的纵向建模表明,退休不会改变主要慢性疾病的风险,但与精神和身体疲劳以及抑郁症状的显著减轻有关,尤其是在患有慢性疾病的人群中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c6a/4787851/f6c8388f3fdb/wesh773226.f1_default.jpg

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