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法国 Gazel 队列中感知健康状况与自我报告疾病之间关联的纵向研究。

Longitudinal study of associations between perceived health status and self reported diseases in the French Gazel cohort.

作者信息

Goldberg P, Guéguen A, Schmaus A, Nakache J P, Goldberg M

机构信息

INSERM U88, HNSM, Saint-Maurice, France.

出版信息

J Epidemiol Community Health. 2001 Apr;55(4):233-8. doi: 10.1136/jech.55.4.233.

DOI:10.1136/jech.55.4.233
PMID:11238577
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1731872/
Abstract

STUDY OBJECTIVE

Although perceived health status is an indicator widely used in epidemiological studies, its relation to various diseases is not well known. The objective of this study is to examine these relations in detail.

DESIGN

Marginal models used for a longitudinal study of the association between three health scales and 47 diseases among 12 164 men and 44 diseases among 4415 women.

SETTING

French Gazel cohort during the period from 1991 to 1996.

MAIN RESULTS

The general health status scale was significantly associated with 43 diseases among men, and 31 among women. Some of these significantly associated diseases were physical (for example, cancer and cerebrovascular accident) and others, psychological (for example, depression). The mental fatigue scale was more specifically associated with psychological disorders, including sleep problems, depression, and nervous diseases. Moreover, modifications in subjects' assessment of their health from one year to the next were generally associated with modifications in reported diseases.

CONCLUSION

Although the mechanism that relates the presence of a disease to perceived health status remains in question, these results show clearly that there is a close association between these two domains that justifies the use of perceived health as a proxy for self reported diseases.

摘要

研究目的

尽管感知健康状况是流行病学研究中广泛使用的一项指标,但其与各种疾病之间的关系尚不明确。本研究的目的是详细探究这些关系。

设计

采用边际模型对12164名男性的三种健康量表与47种疾病、4415名女性的三种健康量表与44种疾病之间的关联进行纵向研究。

研究背景

1991年至1996年期间的法国加泽尔队列研究。

主要结果

总体健康状况量表与男性的43种疾病、女性的31种疾病显著相关。其中一些显著相关的疾病是身体方面的(如癌症和脑血管意外),另一些是心理方面的(如抑郁症)。精神疲劳量表与心理障碍更具特异性关联,包括睡眠问题、抑郁症和神经疾病。此外,受试者对自身健康状况的评估从一年到下一年的变化通常与所报告疾病的变化相关。

结论

尽管疾病的存在与感知健康状况之间的关联机制仍存在疑问,但这些结果清楚地表明,这两个领域之间存在密切关联,这证明了将感知健康作为自我报告疾病的替代指标的合理性。

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