Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555-1019, USA.
Int Immunopharmacol. 2011 May;11(5):589-92. doi: 10.1016/j.intimp.2010.11.016. Epub 2010 Nov 24.
The intestine is the home to a vast diversity of microbiota and a complex of mucosal immune system. Multiple regulatory mechanisms control host immune responses to microbiota and maintain intestinal immune homeostasis. This mini review will provide evidence indicating a Treg cell-IgA axis and such axis playing a major role in maintenance of intestinal homeostasis.
肠道是一个拥有大量微生物群落和复杂黏膜免疫系统的家园。多种调控机制控制着宿主对微生物群的免疫反应，并维持肠道免疫稳态。这篇综述提供了证据表明 Treg 细胞-IgA 轴在维持肠道稳态中起着重要作用。
