Ito Yasuhiro, Miyauchi Akira
Departments of Surgery, Kuma Hospital, 8-2-35, Shimoyamate-dori, Chuo-ku, Kobe City 650-0011, Japan.
J Thyroid Res. 2010 Nov 10;2011:634170. doi: 10.4061/2011/634170.
Papillary carcinoma is a prominent malignancy originating from follicular cells. This disease generally shows an indolent character, but patients demonstrating certain clinicopathological features have a dire prognosis. At present, Western countries adopted almost routine total thyroidectomy with radioactive iodine (RAI) ablation, while limited thyroidectomy with extensive prophylactic lymph node dissection has traditionally been performed for most patients in Japan. Recently, accurate evaluation of carcinoma stage can be performed on preoperative imaging studies, especially on ultrasonography. It is therefore important to treat papillary carcinoma patients depending on clinicopathological features rather than in a stereotyped fashion. In this paper, appropriate extension of thyroidectomy and lymph node dissection is discussed based on Western and recently published Japanese guidelines and the experience in Kuma Hospital.
乳头状癌是一种起源于滤泡细胞的主要恶性肿瘤。这种疾病通常表现为惰性,但具有某些临床病理特征的患者预后较差。目前,西方国家几乎常规采用全甲状腺切除术加放射性碘(RAI)消融,而在日本,大多数患者传统上采用有限的甲状腺切除术加广泛的预防性淋巴结清扫术。最近,术前影像学检查,尤其是超声检查,可以对癌分期进行准确评估。因此,根据临床病理特征而非刻板方式治疗乳头状癌患者非常重要。本文根据西方和最近发表的日本指南以及熊本医院的经验,讨论了甲状腺切除术和淋巴结清扫术的适当扩大范围。