原子力显微镜在视觉科学中的应用。
The applications of atomic force microscopy to vision science.
机构信息
Department of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, Wisconsin, USA.
出版信息
Invest Ophthalmol Vis Sci. 2010 Dec;51(12):6083-94. doi: 10.1167/iovs.10-5470.
Abstract
The atomic force microscope (AFM) is widely used in materials science and has found many applications in biological sciences but has been limited in use in vision science. The AFM can be used to image the topography of soft biological materials in their native environments. It can also be used to probe the mechanical properties of cells and extracellular matrices, including their intrinsic elastic modulus and receptor-ligand interactions. In this review, the operation of the AFM is described along with a review of how it has been thus far used in vision science. It is hoped that this review will serve to stimulate vision scientists to consider incorporating AFM as part of their research toolkit.
摘要
原子力显微镜（AFM）广泛应用于材料科学领域，并在生物科学中找到了许多应用，但在视觉科学中的应用受到限制。AFM 可用于在其天然环境中对软生物材料的形貌进行成像。它还可用于探测细胞和细胞外基质的机械性能，包括它们的固有弹性模量和受体 - 配体相互作用。在这篇综述中，描述了 AFM 的操作原理，并回顾了迄今为止它在视觉科学中的应用。希望这篇综述将有助于激发视觉科学家考虑将 AFM 纳入他们的研究工具包。
相似文献
1
The applications of atomic force microscopy to vision science.原子力显微镜在视觉科学中的应用。
Invest Ophthalmol Vis Sci. 2010 Dec;51(12):6083-94. doi: 10.1167/iovs.10-5470.
2
Atomic force microscopy (AFM).原子力显微镜（AFM）。
Curr Protoc Microbiol. 2008 Feb;Chapter 2:Unit 2C.2. doi: 10.1002/9780471729259.mc02c02s8.
3
Atomic force microscopy as an imaging tool to study the bio/nonbio complexes.原子力显微镜作为一种成像工具，用于研究生物/非生物复合物。
J Microsc. 2020 Dec;280(3):241-251. doi: 10.1111/jmi.12936. Epub 2020 Jun 17.
4
Calculation of Young's modulus value by means of AFM.利用原子力显微镜计算杨氏模量值。
Recent Pat Nanotechnol. 2011 Jan;5(1):27-36. doi: 10.2174/187221011794474985.
5
Imaging and probing cell mechanical properties with the atomic force microscope.利用原子力显微镜成像和探测细胞力学特性
Methods Mol Biol. 2006;319:331-61. doi: 10.1007/978-1-59259-993-6_17.
6
Atomic Force Microscopy: An Introduction.原子力显微镜：简介。
Methods Mol Biol. 2024;2694:295-316. doi: 10.1007/978-1-0716-3377-9_14.
7
Integrated confocal and scanning probe microscopy for biomedical research.用于生物医学研究的集成共聚焦和扫描探针显微镜。
ScientificWorldJournal. 2006 Dec 15;6:1609-18. doi: 10.1100/tsw.2006.269.
8
Atomic force microscopy in biology: technology and techniques.生物学中的原子力显微镜：技术与方法
Biotech Histochem. 2006 Mar-Jun;81(2-3):87-97. doi: 10.1080/10520290600783143.
9
Atomic force microscopy comes of age.原子力显微镜走向成熟。
Biol Cell. 2009 Dec 16;102(2):133-43. doi: 10.1042/BC20090127.
10
Atomic Force Microscopy: An Introduction.原子力显微镜：简介
Methods Mol Biol. 2018;1665:243-258. doi: 10.1007/978-1-4939-7271-5_13.
引用本文的文献
1
The Application of Terahertz Technology in Corneas and Corneal Diseases: A Systematic Review.太赫兹技术在角膜及角膜疾病中的应用：一项系统综述
Bioengineering (Basel). 2025 Jan 8;12(1):45. doi: 10.3390/bioengineering12010045.
2
Nanomechanical thermometry for probing sub-nW thermal transport.用于探测亚纳瓦热传输的纳米机械测温法。
Microsyst Nanoeng. 2024 Oct 18;10(1):148. doi: 10.1038/s41378-024-00770-w.
3
Examination of phacoemulsification tips after different numbers of cataract surgeries.检查不同白内障手术数量后的超声乳化探头。
Sci Rep. 2024 Jul 24;14(1):17092. doi: 10.1038/s41598-024-67891-0.
4
A method for analyzing AFM force mapping data obtained from soft tissue cryosections.一种分析从软组织冷冻切片获得的原子力显微镜力映射数据的方法。
J Biomech. 2024 May;168:112113. doi: 10.1016/j.jbiomech.2024.112113. Epub 2024 Apr 19.
5
Collagen Mimetic Peptides Promote Repair of MMP-1-Damaged Collagen in the Rodent Sclera and Optic Nerve Head.胶原模拟肽促进 MMP-1 损伤的啮齿动物巩膜和视神经头部胶原的修复。
Int J Mol Sci. 2023 Dec 1;24(23):17031. doi: 10.3390/ijms242317031.
6
Advanced Topics in Quantitative Acoustic Microscopy.定量声学显微镜的高级主题。
Adv Exp Med Biol. 2023;1403:253-277. doi: 10.1007/978-3-031-21987-0_12.
7
Review: Advanced Atomic Force Microscopy Modes for Biomedical Research.综述：用于生物医学研究的先进原子力显微镜模式。
Biosensors (Basel). 2022 Dec 2;12(12):1116. doi: 10.3390/bios12121116.
8
Layer-by-Layer Investigation of Ultrastructures and Biomechanics of Human Cornea.逐层研究人眼角膜的超微结构和生物力学。
Int J Mol Sci. 2022 Jul 15;23(14):7833. doi: 10.3390/ijms23147833.
9
Quality control of direct cell-mineral adhesion measurements in air and liquid using inverse AFM imaging.使用反向原子力显微镜成像对空气和液体中细胞与矿物质的直接粘附测量进行质量控制。
RSC Adv. 2021 Jan 28;11(10):5384-5392. doi: 10.1039/d1ra00110h.
10
Nano-Scale Stiffness and Collagen Fibril Deterioration: Probing the Cornea Following Enzymatic Degradation Using Peakforce-QNM AFM.纳米级硬度和胶原纤维恶化：使用峰值力-QNM AFM 探测酶降解后的角膜。
Sensors (Basel). 2021 Feb 26;21(5):1629. doi: 10.3390/s21051629.
本文引用的文献
1
Functionalization of probe tips and supports for single-molecule recognition force microscopy.用于单分子识别力显微镜的探针尖端和支撑物的功能化
Top Curr Chem. 2008;285:29-76. doi: 10.1007/128_2007_24.
2
Single-molecule experiments in biological physics: methods and applications.生物物理学中的单分子实验：方法与应用。
J Phys Condens Matter. 2006 Aug 16;18(32):R531-83. doi: 10.1088/0953-8984/18/32/R01. Epub 2006 Jul 25.
3
Detection of TrkB receptors distributed in cultured hippocampal neurons through bioconjugation between highly luminescent (quantum dot-neutravidin) and (biotinylated anti-TrkB antibody) on neurons by combined atomic force microscope and confocal laser scanning microscope.通过原子力显微镜和共聚焦激光扫描显微镜，将高度发光的量子点-链霉亲和素（quantum dot-neutravidin）与神经元上的（生物素化抗 TrkB 抗体）（biotinylated anti-TrkB antibody）之间的生物共轭，检测培养海马神经元中的 TrkB 受体。
Bioconjug Chem. 2010 Apr 21;21(4):597-603. doi: 10.1021/bc900304b.
4
Single protein molecule mapping with magnetic atomic force microscopy.利用磁原子力显微镜对单个蛋白质分子进行成像。
Biophys J. 2010 Feb 3;98(3):478-87. doi: 10.1016/j.bpj.2009.10.021.
5
Atomic force microscopy comes of age.原子力显微镜走向成熟。
Biol Cell. 2009 Dec 16;102(2):133-43. doi: 10.1042/BC20090127.
6
Atomic force microscopy: a powerful molecular toolkit in nanoproteomics.原子力显微镜：纳米蛋白质组学中的强大分子工具。
Proteomics. 2009 Dec;9(24):5400-5. doi: 10.1002/pmic.200800972.
7
Modeling and analysis of nanoscale interaction forces between Acidithiobacillus ferrooxidans and AFM tip.嗜酸氧化亚铁硫杆菌与原子力显微镜针尖间纳米尺度相互作用力的建模与分析。
Colloids Surf B Biointerfaces. 2010 Jan 1;75(1):310-8. doi: 10.1016/j.colsurfb.2009.09.002. Epub 2009 Sep 8.
8
Force probing surfaces of living cells to molecular resolution.将活细胞表面探测至分子分辨率。
Nat Chem Biol. 2009 Jun;5(6):383-90. doi: 10.1038/nchembio.181.
9
Measuring local surface charge densities in electrolyte solutions with a scanning force microscope.用扫描力显微镜测量电解质溶液中的局部表面电荷密度。
Biophys J. 1992 Aug;63(2):578-82. doi: 10.1016/S0006-3495(92)81601-6.
10
Electrostatic interaction in atomic force microscopy.原子力显微镜中的静电相互作用。
Biophys J. 1991 Oct;60(4):777-85. doi: 10.1016/S0006-3495(91)82112-9.
Zotero 插件