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2010 年 10 月至 11 月刚果暴发急性弛缓性麻痹疫情中 1 型野生脊灰病毒和可能的肠道病毒 109。

Type 1 wild poliovirus and putative enterovirus 109 in an outbreak of acute flaccid paralysis in Congo, October-November 2010.

机构信息

Centre International de Recherches Medicales de Franceville (CIRMF, International Centre of Medical Research of Francville), Franceville, Gabon.

出版信息

Euro Surveill. 2010 Nov 25;15(47):19723. doi: 10.2807/ese.15.47.19723-en.

DOI:10.2807/ese.15.47.19723-en
PMID:21144443
Abstract

An outbreak of flaccid paralysis syndrome in adults is ongoing in Congo. Molecular analysis of faecal, throat and cerebrospinal samples identified wildtype 1 poliovirus and an additional enterovirus C strain related to enterovirus 109 as the cause. As of 22 November, the cumulative number of cases was 409, of which 169 (41.3%) were fatal. This is one of the largest wild type 1 poliovirus outbreaks ever described associated with an unusually high case fatality rate.

摘要

刚果正在爆发成人弛缓性麻痹综合征。对粪便、咽喉和脑脊液样本的分子分析确定,野生型 1 型脊灰病毒和另一种与肠道病毒 109 相关的 C 型肠道病毒是致病原因。截至 11 月 22 日,累计病例数为 409 例,其中 169 例(41.3%)死亡。这是有记录以来最大的一起与异常高病死率相关的野生型 1 型脊灰病毒暴发之一。

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