The University of Melbourne, Department of Clinical and Biomedical Sciences: Barwon Health Victoria, Australia.
J Sci Med Sport. 2011 May;14(3):222-6. doi: 10.1016/j.jsams.2010.10.458. Epub 2010 Dec 13.
Emerging evidence indicates that early life exposures influence adult health outcomes and there is cause to hypothesise a role for physical activity (PA) in childhood as a protective factor in adult depression. This study aimed to investigate the association between self-reported levels of PA in childhood and self-reported depressive illness. Lifetime depression and levels of physical activity (low/high) in childhood (<15 yr) were ascertained by self-report in 2152 adults (20-97 yr) participating in an ongoing epidemiological study in south-eastern Australia. Data were collected between 2000 and 2006. In this sample, 141 women (18.9%) and 169 men (12.0%) reported ever having a depressive episode. Low PA in childhood was associated with an increased risk of reporting depression in adulthood (OR=1.70, 95%CI=1.32-2.17, p<0.001). Adjustment for age, gender and adult PA attenuated the relationship somewhat (OR=1.35, 95%CI=1.01-1.78, p=0.04), however further adjustment for SES or country of birth did not affect this relationship. In this community-based study, lower levels of self-reported PA in childhood were associated with a 35% increase in odds for self-reported depression in adulthood. These results are consistent with the hypothesis that lower levels of PA in childhood may be a risk factor for adult depression.
新出现的证据表明，生命早期的暴露会影响成年后的健康结果，并且有理由假设儿童时期的身体活动（PA）作为成年期抑郁的保护因素发挥作用。本研究旨在调查儿童时期自我报告的 PA 水平与自我报告的抑郁疾病之间的关联。在参与澳大利亚东南部正在进行的一项流行病学研究的 2152 名成年人（20-97 岁）中，通过自我报告确定了儿童时期（<15 岁）的终身抑郁和身体活动（低/高）水平。数据收集于 2000 年至 2006 年之间。在该样本中，141 名女性（18.9%）和 169 名男性（12.0%）报告曾患有抑郁发作。儿童时期低 PA 与成年后报告抑郁的风险增加相关（OR=1.70，95%CI=1.32-2.17，p<0.001）。调整年龄、性别和成人 PA 后，这种关系略有减弱（OR=1.35，95%CI=1.01-1.78，p=0.04），但进一步调整 SES 或出生国并没有影响这种关系。在这项基于社区的研究中，儿童时期自我报告的 PA 水平较低与成年后自我报告的抑郁几率增加 35%相关。这些结果与假设一致，即儿童时期较低的 PA 水平可能是成年期抑郁的一个风险因素。
