Centre for Obesity Research and Epidemiology, Robert Gordon University, Aberdeen, Scotland.
Int J Womens Health. 2010 Nov 10;2:393-9. doi: 10.2147/IJWH.S13456.
Polycystic ovary syndrome (PCOS) affects 2%-26% of women of reproductive age and is often accompanied by obesity. Modest weight loss reduces health risks and ameliorates effects of the syndrome. Weight loss interventions are mainly of short duration and have limited success. A systematic review of the literature was carried out to assess the efficacy of long-term (12 months), nonsurgical weight loss interventions for women with PCOS. Fifteen databases were searched, resulting in eight papers that met the search criteria. Comparison of results and meta-analysis was difficult due to heterogeneity of studies. Behavioral components of interventions were poorly described, and compliance was difficult to ascertain. The results suggested that the inclusion of a lifestyle component improves outcomes, but protocols must be clearly described to maintain study validity and to identify successful behavioral strategies.
多囊卵巢综合征（PCOS）影响着 2%-26%的育龄妇女，且常伴有肥胖。适度减轻体重可降低健康风险并改善该综合征的影响。减肥干预措施主要持续时间较短，且效果有限。对长期（12 个月）非手术减肥干预措施对多囊卵巢综合征妇女的疗效进行了系统评价。检索了 15 个数据库，结果有 8 篇论文符合检索标准。由于研究存在异质性，因此比较结果和进行荟萃分析较为困难。干预措施的行为组成部分描述较差，难以确定依从性。结果表明，纳入生活方式组成部分可改善结局，但必须清楚地描述方案，以保持研究的有效性并确定成功的行为策略。
