The discovery of salinosporamide K from the marine bacterium "Salinispora pacifica" by genome mining gives insight into pathway evolution.
作者信息
Eustáquio Alessandra S, Nam Sang-Jip, Penn Kevin, Lechner Anna, Wilson Micheal C, Fenical William, Jensen Paul R, Moore Bradley S
机构信息
Scripps Institution of Oceanography, University of California at San Diego, La Jolla, CA 92093-0204, USA.
出版信息
Chembiochem. 2011 Jan 3;12(1):61-4. doi: 10.1002/cbic.201000564.
Abstract
摘要
相似文献
1
The discovery of salinosporamide K from the marine bacterium "Salinispora pacifica" by genome mining gives insight into pathway evolution.通过基因组挖掘从海洋细菌“太平洋盐孢菌”中发现盐孢酰胺K，这为代谢途径的进化提供了见解。
Chembiochem. 2011 Jan 3;12(1):61-4. doi: 10.1002/cbic.201000564.
2
Molecular networking and pattern-based genome mining improves discovery of biosynthetic gene clusters and their products from Salinispora species.分子网络和基于模式的基因组挖掘有助于从盐孢菌属物种中发现生物合成基因簇及其产物。
Chem Biol. 2015 Apr 23;22(4):460-471. doi: 10.1016/j.chembiol.2015.03.010. Epub 2015 Apr 9.
3
FW0622, a new siderophore isolated from marine sp. by genomic mining.FW0622，一种从海洋 中通过基因组挖掘得到的新型铁载体。
Nat Prod Res. 2020 Nov;34(21):3082-3088. doi: 10.1080/14786419.2019.1608541. Epub 2019 May 10.
4
Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica.基因组测序揭示了热带盐孢菌这一海洋放线菌中的复杂次生代谢组。
Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10376-81. doi: 10.1073/pnas.0700962104. Epub 2007 Jun 11.
5
Evolution of secondary metabolite genes in three closely related marine actinomycete species.三种亲缘关系密切的海洋放线菌中次生代谢基因的进化。
Appl Environ Microbiol. 2011 Oct;77(20):7261-70. doi: 10.1128/AEM.05943-11. Epub 2011 Aug 26.
6
Engineered biosynthesis of antiprotealide and other unnatural salinosporamide proteasome inhibitors.抗蛋白酶抑制肽及其他非天然盐孢菌素蛋白酶体抑制剂的工程化生物合成。
J Am Chem Soc. 2008 Jun 25;130(25):7822-3. doi: 10.1021/ja8029398. Epub 2008 May 31.
7
Biosynthetic convergence of salinosporamides A and B in the marine actinomycete Salinispora tropica.海洋放线菌热带盐孢菌中盐孢菌素A和B的生物合成汇聚
Org Lett. 2007 Mar 1;9(5):845-8. doi: 10.1021/ol063102o. Epub 2007 Feb 3.
8
Vertical Inheritance Facilitates Interspecies Diversification in Biosynthetic Gene Clusters and Specialized Metabolites.垂直遗传促进生物合成基因簇和特化代谢物的种间多样化。
mBio. 2021 Dec 21;12(6):e0270021. doi: 10.1128/mBio.02700-21. Epub 2021 Nov 23.
9
Microdiversity and evidence for high dispersal rates in the marine actinomycete 'Salinispora pacifica'.海洋放线菌“盐生拟诺卡氏菌”的微观多样性和高分散率的证据。
Environ Microbiol. 2012 Feb;14(2):480-93. doi: 10.1111/j.1462-2920.2011.02641.x. Epub 2011 Nov 28.
10
Genomic insights into specialized metabolism in the marine actinomycete Salinispora.海洋放线菌盐孢菌中特殊代谢的基因组学见解。
Environ Microbiol. 2017 Sep;19(9):3660-3673. doi: 10.1111/1462-2920.13867. Epub 2017 Aug 14.
引用本文的文献
1
Exploring omics strategies for drug discovery from isolated from the marine ecosystem.探索从海洋生态系统中分离出来用于药物发现的组学策略。
Front Pharmacol. 2025 Aug 15;16:1634207. doi: 10.3389/fphar.2025.1634207. eCollection 2025.
2
Biosynthetic gene profiling and genomic potential of the novel photosynthetic marine bacterium .新型光合海洋细菌的生物合成基因谱分析与基因组潜力
Front Microbiol. 2023 Sep 29;14:1238779. doi: 10.3389/fmicb.2023.1238779. eCollection 2023.
3
An Unprecedented Number of Cytochrome P450s Are Involved in Secondary Metabolism in Species.前所未有的大量细胞色素P450参与物种的次生代谢。
Microorganisms. 2022 Apr 21;10(5):871. doi: 10.3390/microorganisms10050871.
4
Exploring Newer Biosynthetic Gene Clusters in Marine Microbial Prospecting.海洋微生物勘探中新型生物合成基因簇的探索。
Mar Biotechnol (NY). 2022 Jun;24(3):448-467. doi: 10.1007/s10126-022-10118-y. Epub 2022 Apr 8.
5
Vertical Inheritance Facilitates Interspecies Diversification in Biosynthetic Gene Clusters and Specialized Metabolites.垂直遗传促进生物合成基因簇和特化代谢物的种间多样化。
mBio. 2021 Dec 21;12(6):e0270021. doi: 10.1128/mBio.02700-21. Epub 2021 Nov 23.
6
Genome mining methods to discover bioactive natural products.基因组挖掘方法发现生物活性天然产物。
Nat Prod Rep. 2021 Nov 17;38(11):2100-2129. doi: 10.1039/d1np00032b.
7
Insights into Red Sea Brine Pool Specialized Metabolism Gene Clusters Encoding Potential Metabolites for Biotechnological Applications and Extremophile Survival.洞察红海盐水池特化代谢基因簇，这些基因簇编码潜在的生物技术应用和极端微生物生存的代谢产物。
Mar Drugs. 2019 May 8;17(5):273. doi: 10.3390/md17050273.
8
Asymmetric Alkene and Arene Halofunctionalization Reactions in Meroterpenoid Biosynthesis.聚酮萜类生物合成中的不对称烯烃和芳烃卤官能化反应。
Synlett. 2018 Mar;29(4):401-409. doi: 10.1055/s-0036-1590919. Epub 2017 Sep 27.
9
Antibacterial and anticancer activities of orphan biosynthetic gene clusters from Atlantis II Red Sea brine pool.源自 Atlantis II 红海盐湖的孤儿生物合成基因簇的抗菌和抗癌活性。
Microb Cell Fact. 2019 Mar 18;18(1):56. doi: 10.1186/s12934-019-1103-3.
10
Genomic insights into specialized metabolism in the marine actinomycete Salinispora.海洋放线菌盐孢菌中特殊代谢的基因组学见解。
Environ Microbiol. 2017 Sep;19(9):3660-3673. doi: 10.1111/1462-2920.13867. Epub 2017 Aug 14.
本文引用的文献
1
Engineering fluorometabolite production: fluorinase expression in Salinispora tropica Yields Fluorosalinosporamide.工程化氟代谢产物的生产：在盐单胞菌属 tropica 中表达氟酶产生氟沙利诺菌素。
J Nat Prod. 2010 Mar 26;73(3):378-82. doi: 10.1021/np900719u.
2
Biosynthesis of salinosporamides from alpha,beta-unsaturated fatty acids: implications for extending polyketide synthase diversity.源自α,β-不饱和脂肪酸的盐孢菌素的生物合成：对扩展聚酮合酶多样性的意义
J Am Chem Soc. 2009 Aug 5;131(30):10376-7. doi: 10.1021/ja9042824.
3
Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine.由S-腺苷-L-甲硫氨酸生物合成盐孢霉素A聚酮合酶底物氯乙基丙二酰辅酶A。
Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12295-300. doi: 10.1073/pnas.0901237106. Epub 2009 Jul 9.
4
Discovery and development of the anticancer agent salinosporamide A (NPI-0052).抗癌药物沙利诺酰胺A（NPI-0052）的发现与开发。
Bioorg Med Chem. 2009 Mar 15;17(6):2175-80. doi: 10.1016/j.bmc.2008.10.075. Epub 2008 Nov 5.
5
Evolution of polyketide synthases in bacteria.细菌中聚酮合酶的进化
Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4595-600. doi: 10.1073/pnas.0710107105. Epub 2008 Feb 4.
6
Discovery and characterization of a marine bacterial SAM-dependent chlorinase.一种海洋细菌依赖S-腺苷甲硫氨酸的二氢卟吩酶的发现与特性研究
Nat Chem Biol. 2008 Jan;4(1):69-74. doi: 10.1038/nchembio.2007.56. Epub 2007 Dec 2.
7
Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica.基因组测序揭示了热带盐孢菌这一海洋放线菌中的复杂次生代谢组。
Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10376-81. doi: 10.1073/pnas.0700962104. Epub 2007 Jun 11.
8
Biosynthetic convergence of salinosporamides A and B in the marine actinomycete Salinispora tropica.海洋放线菌热带盐孢菌中盐孢菌素A和B的生物合成汇聚
Org Lett. 2007 Mar 1;9(5):845-8. doi: 10.1021/ol063102o. Epub 2007 Feb 3.
9
Cinnabaramides A-G: analogues of lactacystin and salinosporamide from a terrestrial streptomycete.肉桂酰胺A - G：来自一种陆生链霉菌的乳胞素和盐孢菌素类似物。
J Nat Prod. 2007 Feb;70(2):246-52. doi: 10.1021/np060162u. Epub 2007 Jan 24.
10
Species-specific secondary metabolite production in marine actinomycetes of the genus Salinispora.盐孢菌属海洋放线菌中特定物种的次生代谢产物合成
Appl Environ Microbiol. 2007 Feb;73(4):1146-52. doi: 10.1128/AEM.01891-06. Epub 2006 Dec 8.
Zotero 插件