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The discovery of salinosporamide K from the marine bacterium "Salinispora pacifica" by genome mining gives insight into pathway evolution.

作者信息

Eustáquio Alessandra S, Nam Sang-Jip, Penn Kevin, Lechner Anna, Wilson Micheal C, Fenical William, Jensen Paul R, Moore Bradley S

机构信息

Scripps Institution of Oceanography, University of California at San Diego, La Jolla, CA 92093-0204, USA.

出版信息

Chembiochem. 2011 Jan 3;12(1):61-4. doi: 10.1002/cbic.201000564.

DOI:10.1002/cbic.201000564
PMID:21154492
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3088357/
Abstract
摘要

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本文引用的文献

1
Engineering fluorometabolite production: fluorinase expression in Salinispora tropica Yields Fluorosalinosporamide.工程化氟代谢产物的生产:在盐单胞菌属 tropica 中表达氟酶产生氟沙利诺菌素。
J Nat Prod. 2010 Mar 26;73(3):378-82. doi: 10.1021/np900719u.
2
Biosynthesis of salinosporamides from alpha,beta-unsaturated fatty acids: implications for extending polyketide synthase diversity.源自α,β-不饱和脂肪酸的盐孢菌素的生物合成:对扩展聚酮合酶多样性的意义
J Am Chem Soc. 2009 Aug 5;131(30):10376-7. doi: 10.1021/ja9042824.
3
Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine.由S-腺苷-L-甲硫氨酸生物合成盐孢霉素A聚酮合酶底物氯乙基丙二酰辅酶A。
Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12295-300. doi: 10.1073/pnas.0901237106. Epub 2009 Jul 9.
4
Discovery and development of the anticancer agent salinosporamide A (NPI-0052).抗癌药物沙利诺酰胺A(NPI-0052)的发现与开发。
Bioorg Med Chem. 2009 Mar 15;17(6):2175-80. doi: 10.1016/j.bmc.2008.10.075. Epub 2008 Nov 5.
5
Evolution of polyketide synthases in bacteria.细菌中聚酮合酶的进化
Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4595-600. doi: 10.1073/pnas.0710107105. Epub 2008 Feb 4.
6
Discovery and characterization of a marine bacterial SAM-dependent chlorinase.一种海洋细菌依赖S-腺苷甲硫氨酸的二氢卟吩酶的发现与特性研究
Nat Chem Biol. 2008 Jan;4(1):69-74. doi: 10.1038/nchembio.2007.56. Epub 2007 Dec 2.
7
Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica.基因组测序揭示了热带盐孢菌这一海洋放线菌中的复杂次生代谢组。
Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10376-81. doi: 10.1073/pnas.0700962104. Epub 2007 Jun 11.
8
Biosynthetic convergence of salinosporamides A and B in the marine actinomycete Salinispora tropica.海洋放线菌热带盐孢菌中盐孢菌素A和B的生物合成汇聚
Org Lett. 2007 Mar 1;9(5):845-8. doi: 10.1021/ol063102o. Epub 2007 Feb 3.
9
Cinnabaramides A-G: analogues of lactacystin and salinosporamide from a terrestrial streptomycete.肉桂酰胺A - G:来自一种陆生链霉菌的乳胞素和盐孢菌素类似物。
J Nat Prod. 2007 Feb;70(2):246-52. doi: 10.1021/np060162u. Epub 2007 Jan 24.
10
Species-specific secondary metabolite production in marine actinomycetes of the genus Salinispora.盐孢菌属海洋放线菌中特定物种的次生代谢产物合成
Appl Environ Microbiol. 2007 Feb;73(4):1146-52. doi: 10.1128/AEM.01891-06. Epub 2006 Dec 8.