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用于调强放射治疗预处理验证的商业门静脉剂量测定软件的实施与验证

Implementation and validation of a commercial portal dosimetry software for intensity-modulated radiation therapy pre-treatment verification.

作者信息

Varatharaj C, Moretti Eugenia, Ravikumar M, Malisan Maria Rosa, Supe Sanjay S, Padovani Renato

机构信息

Department of Medical Physics, University Hospital, Udine - 33100, India.

出版信息

J Med Phys. 2010 Oct;35(4):189-96. doi: 10.4103/0971-6203.71758.

DOI:10.4103/0971-6203.71758
PMID:21170182
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2990112/
Abstract

Electronic portal imaging devices (EPIDs) are extensively used for obtaining dosimetric information of pre-treatment field verification and in-vivo dosimetry for intensity-modulated radiotherapy (IMRT). In the present study, we have implemented the newly developed portal dosimetry software using independent dose prediction algorithm EPIDose(™) and evaluated this new tool for the pre-treatment IMRT plan quality assurance of Whole Pelvis with Simultaneous Integrated Boost (WP-SIB-IMRT) of prostate cases by comparing with routine two-dimensional (2D) array detector system (MapCHECK(™)). We have investigated 104 split fields using γ -distributions in terms of predefined γ frequency parameters. The mean γ values are found to be 0.42 (SD: 0.06) and 0.44 (SD: 0.06) for the EPIDose and MapCHECK(™), respectively. The average γ∆ for EPIDose and MapCHECK(™) are found as 0.51 (SD: 0.06) and 0.53 (SD: 0.07), respectively. Furthermore, the percentage of points with γ < 1, γ < 1.5, and γ > 2 are 97.4%, 99.3%, and 0.56%, respectively for EPIDose and 96.4%, 99.0% and 0.62% for MapCHECK(™). Based on our results obtained with EPIDose and strong agreement with MapCHECK(™), we may conclude that the EPIDose portal dosimetry system has been successfully implemented and validated with our routine 2D array detector.

摘要

电子射野影像装置（EPID）被广泛用于获取调强放疗（IMRT）预处理射野验证和体内剂量测定的剂量学信息。在本研究中，我们使用独立剂量预测算法EPIDose(™)实现了新开发的射野剂量测定软件，并通过与常规二维（2D）阵列探测器系统（MapCHECK(™)）比较，评估了该新工具用于前列腺癌病例全盆腔同步整合加量调强放疗（WP-SIB-IMRT）预处理IMRT计划质量保证的效果。我们根据预定义的γ频率参数，使用γ分布研究了104个分割野。发现EPIDose和MapCHECK(™)的平均γ值分别为0.42（标准差：0.06）和0.44（标准差：0.06）。EPIDose和MapCHECK(™)的平均γ∆分别为0.51（标准差：0.06）和0.53（标准差：0.07）。此外，对于EPIDose，γ<1、γ<1.5和γ>2的点的百分比分别为97.4%、99.3%和0.56%，对于MapCHECK(™)分别为96.4%、99.0%和0.62%。基于我们使用EPIDose获得的结果以及与MapCHECK(™)的高度一致性，我们可以得出结论，EPIDose射野剂量测定系统已成功实施并通过我们的常规2D阵列探测器进行了验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c263/2990112/1a5a9b3045d0/JMP-35-189-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c263/2990112/572f6aba4637/JMP-35-189-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c263/2990112/f704fc8ac2fa/JMP-35-189-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c263/2990112/efad27ca7725/JMP-35-189-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c263/2990112/3d08d414a26e/JMP-35-189-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c263/2990112/1e403bb21aa7/JMP-35-189-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c263/2990112/1a5a9b3045d0/JMP-35-189-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c263/2990112/572f6aba4637/JMP-35-189-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c263/2990112/f704fc8ac2fa/JMP-35-189-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c263/2990112/efad27ca7725/JMP-35-189-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c263/2990112/3d08d414a26e/JMP-35-189-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c263/2990112/1e403bb21aa7/JMP-35-189-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c263/2990112/1a5a9b3045d0/JMP-35-189-g006.jpg

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