Department of Radiation Oncology, Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute, Mumbai-400053, India.
J Appl Clin Med Phys. 2010 Aug 19;11(4):3268. doi: 10.1120/jacmp.v11i4.3268.
Portal dosimetry (PD) was performed for 181 fields from 14 IMRT plans of various clinical sites at gantry zero and source-to-detector distance (SDD) of 100 cm. PD was realized using aSi1000 electronic portal imaging device (EPID) and portal dose prediction (PDP) algorithm implemented in Eclipse treatment planning system (TPS). Agreement of PDP predicted and EPID measured photon fluence/dose distribution were evaluated using gamma (γ) index set at 3% at 3 mm distance to point agreement (DTA). Three gamma scaling parameters, maximum γ (γ(max)), average γ (γ(avg)) and percentage of points with γ ≤ 1 (γ% ≤ 1) were estimated for each field. An independent measurement was carried out using MatriXX 2D ion chamber array with detector plane at 100 cm and γ(max), γ(avg) and γ% ≤ 1 were estimated using OmniPro IMRT analyzing software. Effect of extended SDD and gantry rotation on portal dosimetry outcome was also investigated for another 45 IMRT fields. PDP predicted and EPID measured photon fluence agrees well with overall mean values of γ(max), γ(avg) and γ% ≤ 1 at 2.02, 0.24 and 99.43%, respectively. γ(max) value was lower in 15 MV compared to 6 MV IMRT plan. Independent verification using MatriXX showed comparable overall mean values of γ(avg) and γ% ≤ 1 at 0.25 and 99.80%. However, in all plans, MatriXX showed significantly lower γ(max) (p < 0.05) with an overall mean value of 1.35. In portal dosimetry, compared to gamma values at 100 cm SDD, γ(max), γ(avg) and γ% ≤ 1 values improve from a mean of 0.16, 0.03 and 0.26 at 110 cm SDD to 0.35, 0.05 and 0.29 at 140 cm SDD. PD outcome was independent of gantry rotation. In conclusion, both MatriXX 2D ion chamber array and portal dosimetry showed comparable results and can be use as an alternative to each other for relative photon fluence verification.
在零机架角度和源到探测器距离(SDD)为 100 厘米的情况下,对来自 14 个不同临床部位的 181 个调强放疗计划进行了门户剂量测定(PD)。PD 使用 aSi1000 电子门户成像设备(EPID)和 Eclipse 治疗计划系统(TPS)中实现的门户剂量预测(PDP)算法进行。使用 3%的 3 毫米点吻合γ(γ)指数集评估 PDP 预测和 EPID 测量的光子通量/剂量分布的一致性。为每个场估计了三个γ缩放参数,最大γ(γ(max))、平均γ(γ(avg))和γ≤1 的点百分比(γ%≤1)。使用探测器平面位于 100 厘米处的 MatriXX 2D 离子室阵列进行独立测量,并使用 OmniPro IMRT 分析软件估计γ(max)、γ(avg)和γ%≤1。还研究了扩展 SDD 和机架旋转对门户剂量测定结果的影响,对另外 45 个调强放疗场进行了研究。PDP 预测和 EPID 测量的光子通量与γ(max)、γ(avg)和γ%≤1 的总体平均值吻合良好,分别为 2.02%、0.24%和 99.43%。与 6MV 调强放疗计划相比,15MV 的γ(max)值较低。使用 MatriXX 进行的独立验证显示,γ(avg)和γ%≤1 的总体平均值相当,分别为 0.25%和 99.80%。然而,在所有计划中,MatriXX 显示γ(max)显著降低(p<0.05),总体平均值为 1.35。在门户剂量测定中,与 100 厘米 SDD 的γ值相比,γ(max)、γ(avg)和γ%≤1 值从 110 厘米 SDD 的平均值 0.16、0.03 和 0.26 提高到 140 厘米 SDD 的 0.35、0.05 和 0.29。PD 结果与机架旋转无关。总之,MatriXX 2D 离子室阵列和门户剂量测定都显示出了可比的结果,可以相互替代,用于相对光子通量验证。