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间质性肺疾病中淋巴细胞性肺泡炎的特征及临床意义

Characteristics and clinical significance of the lymphocytic alveolitis in interstitial lung disorders.

作者信息

Rossi G A, Balbi B, Lantero S, Ravazzoni C

机构信息

1. Div. di Pneumologia, Ospedale, San Martino, Genova, Italy.

出版信息

Lung. 1990;168 Suppl:957-63. doi: 10.1007/BF02718233.

DOI:10.1007/BF02718233
PMID:2117216
Abstract

Although the mechanisms responsible for lung damage and respiratory function deterioration for each type of alveolitis are not entirely known, with the opportunity to study the cells present in the lower respiratory tract, their functions and the mediators released in different conditions, we will be able to better understand the link between the inflammatory process, the acute tissue damage, the progression of the disease and the pulmonary scarring. This knowledge will be helpful in a better management of patients with interstitial lung diseases modulated by immunologic mechanisms.

摘要

虽然每种类型的肺泡炎导致肺损伤和呼吸功能恶化的机制尚不完全清楚,但有机会研究下呼吸道中存在的细胞、它们的功能以及在不同条件下释放的介质,我们将能够更好地理解炎症过程、急性组织损伤、疾病进展和肺瘢痕形成之间的联系。这些知识将有助于更好地管理由免疫机制介导的间质性肺疾病患者。

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Characteristics and clinical significance of the lymphocytic alveolitis in interstitial lung disorders.间质性肺疾病中淋巴细胞性肺泡炎的特征及临床意义
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本文引用的文献

1
Bronchoalveolar lavage fluid cell counts in cryptogenic fibrosing alveolitis and their relation to therapy.隐源性纤维性肺泡炎的支气管肺泡灌洗液体细胞计数及其与治疗的关系。
Thorax. 1980 May;35(5):328-39. doi: 10.1136/thx.35.5.328.
2
Bronchoalveolar lavage in pulmonary fibrosis: comparison of cells obtained with lung biopsy and clinical features.肺纤维化中的支气管肺泡灌洗:与肺活检获取的细胞及临床特征的比较
Thorax. 1980 Jan;35(1):9-18. doi: 10.1136/thx.35.1.9.
3
Fibronectin in human bronchopulmonary lavage fluid. Elevation in patients with interstitial lung disease.
人支气管肺泡灌洗液中的纤连蛋白。间质性肺疾病患者升高。
J Clin Invest. 1982 Jan;69(1):113-22. doi: 10.1172/jci110421.
4
Bronchoalveolar cells in advanced pulmonary sarcoidosis.晚期肺结节病中的支气管肺泡细胞。
Am Rev Respir Dis. 1981 Jul;124(1):9-12. doi: 10.1164/arrd.1981.124.1.9.
5
Immune reactions in the lungs of asymptomatic dairy farmers.无症状奶农肺部的免疫反应。
Am Rev Respir Dis. 1982 Dec;126(6):964-7. doi: 10.1164/arrd.1982.126.6.964.
6
Mechanisms of hypergammaglobulinemia in pulmonary sarcoidosis. Site of increased antibody production and role of T lymphocytes.肺结节病中高丙种球蛋白血症的机制。抗体产生增加的部位及T淋巴细胞的作用。
J Clin Invest. 1981 Jan;67(1):86-92. doi: 10.1172/JCI110036.
7
Maintenance of granuloma formation in pulmonary sarcoidosis by T lymphocytes within the lung.肺内T淋巴细胞维持肺结节病中的肉芽肿形成。
N Engl J Med. 1980 Mar 13;302(11):594-8. doi: 10.1056/NEJM198003133021102.
8
Mechanisms of pulmonary fibrosis. Spontaneous release of the alveolar macrophage-derived growth factor in the interstitial lung disorders.肺纤维化的机制。间质性肺疾病中肺泡巨噬细胞衍生生长因子的自发释放。
J Clin Invest. 1983 Nov;72(5):1801-13. doi: 10.1172/JCI111140.
9
Release of interleukin-1 by alveolar macrophages of patients with active pulmonary sarcoidosis.活动期结节病患者肺泡巨噬细胞释放白细胞介素-1 。
Am Rev Respir Dis. 1984 Apr;129(4):569-72.
10
The alveolitis of pulmonary sarcoidosis. Evaluation of natural history and alveolitis-dependent changes in lung function.肺结节病的肺泡炎。自然病程及依赖肺泡炎的肺功能变化评估。
Am Rev Respir Dis. 1983 Aug;128(2):256-65. doi: 10.1164/arrd.1983.128.2.256.